Bronchoscopic interventions for bronchopleural fistulas

Bronchopleural fistula is a potentially fatal disease most often caused after pneumonectomy. Concomitant problems such as pulmonary infection and respiratory failure are typically the main contributors to patient mortality because of the improper contact between the bronchial and pleural cavity. The...

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Main Authors: Lingli Jin, Yaqing Li
Format: Article
Language:English
Published: SAGE Publishing 2023-04-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/17534666231164541
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author Lingli Jin
Yaqing Li
author_facet Lingli Jin
Yaqing Li
author_sort Lingli Jin
collection DOAJ
description Bronchopleural fistula is a potentially fatal disease most often caused after pneumonectomy. Concomitant problems such as pulmonary infection and respiratory failure are typically the main contributors to patient mortality because of the improper contact between the bronchial and pleural cavity. Therefore, bronchopleural fistulas need immediate treatment, which requires the accurate location and timely closure of the fistula. Currently, bronchoscopic interventions, because of their flexibility and versatility, are reliable alternative therapies in patients for whom surgical intervention is unsuitable. Possible interventions include bronchoscopic placement of blocking agents, atrial septal defect (ASD)/ventricular septal defect (VSD) occluders, airway stents, endobronchial valves (EBVs) and endobronchial Watanabe spigots (EWSs). Recent developments in mesenchymal stem cells (MSCs) transplantation technology and three-dimensional (3D) printed stents have also contributed to the treatment of bronchopleural fistula, but more research is needed to investigate the long-term benefits. This review focuses on the effectiveness of various bronchoscopic measures for the treatment of bronchopleural fistula and the directions for future development.
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spelling doaj.art-d43d3ed39231461080c3bbe177aefd572023-04-17T12:33:40ZengSAGE PublishingTherapeutic Advances in Respiratory Disease1753-46662023-04-011710.1177/17534666231164541Bronchoscopic interventions for bronchopleural fistulasLingli JinYaqing LiBronchopleural fistula is a potentially fatal disease most often caused after pneumonectomy. Concomitant problems such as pulmonary infection and respiratory failure are typically the main contributors to patient mortality because of the improper contact between the bronchial and pleural cavity. Therefore, bronchopleural fistulas need immediate treatment, which requires the accurate location and timely closure of the fistula. Currently, bronchoscopic interventions, because of their flexibility and versatility, are reliable alternative therapies in patients for whom surgical intervention is unsuitable. Possible interventions include bronchoscopic placement of blocking agents, atrial septal defect (ASD)/ventricular septal defect (VSD) occluders, airway stents, endobronchial valves (EBVs) and endobronchial Watanabe spigots (EWSs). Recent developments in mesenchymal stem cells (MSCs) transplantation technology and three-dimensional (3D) printed stents have also contributed to the treatment of bronchopleural fistula, but more research is needed to investigate the long-term benefits. This review focuses on the effectiveness of various bronchoscopic measures for the treatment of bronchopleural fistula and the directions for future development.https://doi.org/10.1177/17534666231164541
spellingShingle Lingli Jin
Yaqing Li
Bronchoscopic interventions for bronchopleural fistulas
Therapeutic Advances in Respiratory Disease
title Bronchoscopic interventions for bronchopleural fistulas
title_full Bronchoscopic interventions for bronchopleural fistulas
title_fullStr Bronchoscopic interventions for bronchopleural fistulas
title_full_unstemmed Bronchoscopic interventions for bronchopleural fistulas
title_short Bronchoscopic interventions for bronchopleural fistulas
title_sort bronchoscopic interventions for bronchopleural fistulas
url https://doi.org/10.1177/17534666231164541
work_keys_str_mv AT linglijin bronchoscopicinterventionsforbronchopleuralfistulas
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