CobB-mediated deacetylation of the chaperone CesA regulates Escherichia coli O157:H7 virulence

CobB-mediated deacetylation of the chaperone CesA regulates Escherichia coli O157:H7 virulence

ABSTRACTEnterohemorrhagic Escherichia coli (EHEC) O157:H7 is a common food-borne pathogen that can cause acute diseases. Lysine acetylation is a post-translational modification (PTM) that occurs in various prokaryotes and is regulated by CobB, the only deacetylase found in bacteria. Here, we demonst...

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Bibliographic Details
Main Authors: Linxing Li, Bin Yang, Jing Wang, Yi Wei, Binbin Xiang, Yutao Liu, Pan Wu, Wanwu Li, Yanling Wang, Xinyu Zhao, Jingliang Qin, Miaomiao Liu, Ruiying Liu, Guozhen Ma, Tian Fu, Min Wang, Bin Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
CobB
deacetylation
CesA
EspA
virulence
EHEC
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2331435

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