Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance

How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge. The occurrence of the “CRISPR babies” in 2018 publicly brought this issue into sharp focus, and led...

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Main Authors: Leifan Wang, Lijun Shang, Weiwen Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Journal of Biosafety and Biosecurity
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2588933822000280
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author Leifan Wang
Lijun Shang
Weiwen Zhang
author_facet Leifan Wang
Lijun Shang
Weiwen Zhang
author_sort Leifan Wang
collection DOAJ
description How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge. The occurrence of the “CRISPR babies” in 2018 publicly brought this issue into sharp focus, and led to comprehensive regulatory reforms in China and various countries around the world. The current article analyzes this event-driven regulatory reform in China by elaborating the most salient provisions designed to prevent risk and protect individual rights, public health, and social morality relating to human genome editing in four important sectors of law: biosecurity law, civil code, criminal law and patent law. It highlights that, although regulation is being undertaken, the gaps between the law and advancing technology remain discernible, at both a national and transnational level (i.e., the “double-pacing problem”). Further attention and collaboration will be required to address the ongoing challenges associated with the use of human genome editing.
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spelling doaj.art-d4405f2065164a988138026ea178bb8c2023-04-20T04:37:36ZengKeAi Communications Co., Ltd.Journal of Biosafety and Biosecurity2588-93382023-03-0151813Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governanceLeifan Wang0Lijun Shang1Weiwen Zhang2Tianjin University School of Law, Tianjin 300072, China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin 300072, China; Corresponding author at: Tianjin University School of Law, Tianjin 300072, China.School of Human Sciences, London Metropolitan University, London N7 8DB, UK; Biological Security Research Centre, Metropolitan University, London N7 8DB, UKCenter for Biosafety Research and Strategy, Tianjin University, Tianjin 300072, China; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, ChinaHow to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge. The occurrence of the “CRISPR babies” in 2018 publicly brought this issue into sharp focus, and led to comprehensive regulatory reforms in China and various countries around the world. The current article analyzes this event-driven regulatory reform in China by elaborating the most salient provisions designed to prevent risk and protect individual rights, public health, and social morality relating to human genome editing in four important sectors of law: biosecurity law, civil code, criminal law and patent law. It highlights that, although regulation is being undertaken, the gaps between the law and advancing technology remain discernible, at both a national and transnational level (i.e., the “double-pacing problem”). Further attention and collaboration will be required to address the ongoing challenges associated with the use of human genome editing.http://www.sciencedirect.com/science/article/pii/S2588933822000280Human genome editingCRISPR babiesDouble-pacing problemCollaborative governanceChina
spellingShingle Leifan Wang
Lijun Shang
Weiwen Zhang
Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
Journal of Biosafety and Biosecurity
Human genome editing
CRISPR babies
Double-pacing problem
Collaborative governance
China
title Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
title_full Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
title_fullStr Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
title_full_unstemmed Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
title_short Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
title_sort human genome editing after the crispr babies the double pacing problem and collaborative governance
topic Human genome editing
CRISPR babies
Double-pacing problem
Collaborative governance
China
url http://www.sciencedirect.com/science/article/pii/S2588933822000280
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AT weiwenzhang humangenomeeditingafterthecrisprbabiesthedoublepacingproblemandcollaborativegovernance