Steroid-resistant nephrotic syndrome associated with certain SGPL1 variants in a family: Case report and literature review

Steroid-resistant nephrotic syndrome associated with certain SGPL1 variants in a family: Case report and literature review

ObjectivesSteroid-resistant nephrotic syndrome (SRNS) is a clinical syndrome characterized by the lack of response to standard steroid therapy, usually progressing to end-stage renal disease. We reported two cases of female identical twins with SRNS caused by SGPL1 variants in one family, reviewed t...

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Bibliographic Details
Main Authors: Siying Yang, Yonghua He, Jianhua Zhou, Huiqing Yuan, Liru Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pediatrics
Subjects:
steroid-resistant nephrotic syndrome
proteinuria
SGPL1 gene mutation
clinical phenotype
genotype
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1079758/full

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