Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020
<i>Background</i>: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and progressive condition; however, the true characteristics of CTEPH are still unknown, as notable regional variations exist in terms of patients’ age, baseline hemodynamic data, and management choices. T...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/8/1426 |
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| author | Ričards Kauliņš Ainārs Rudzītis Aivars Lejnieks Dana Kigitoviča Andris Skride |
| author_facet | Ričards Kauliņš Ainārs Rudzītis Aivars Lejnieks Dana Kigitoviča Andris Skride |
| author_sort | Ričards Kauliņš |
| collection | DOAJ |
| description | <i>Background</i>: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and progressive condition; however, the true characteristics of CTEPH are still unknown, as notable regional variations exist in terms of patients’ age, baseline hemodynamic data, and management choices. This report aims to investigate the baseline clinical characteristics, incidence, and risk factors associated with CTEPH patients in Latvia from 2019 to 2020. <i>Methods</i>: The data were analyzed from a prospective, nationwide, Latvian pulmonary hypertension registry for incident CTEPH cases. The patients’ clinical characteristics were assessed at the time of diagnosis. <i>Results</i>: During the course of this study, a cohort of 13 patients with CTEPH were included for analysis. Among the enrolled CTEPH patients, most exhibited low exercise and functional capacity, with a median (±IQR) 6 min walk distance of 300.0 (±150.0) m. The median values (±IQR) for mean pulmonary artery pressure and pulmonary vascular resistance were 40.0 ± 13.0 mmHg and 7.35 ± 2.82 Wood units, respectively. The most common risk factors for CTEPH were a history of acute pulmonary embolism and a blood group other than O. <i>Conclusions</i>: The findings of this report revealed the characteristics of the Latvian CTEPH population, indicating that a significant proportion of patients are elderly individuals with multiple comorbidities. |
| first_indexed | 2024-03-10T23:46:00Z |
| format | Article |
| id | doaj.art-d448c2098a5c42138c08b4790417f1cf |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T23:46:00Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-d448c2098a5c42138c08b4790417f1cf2023-11-19T02:06:06ZengMDPI AGMedicina1010-660X1648-91442023-08-01598142610.3390/medicina59081426Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020Ričards Kauliņš0Ainārs Rudzītis1Aivars Lejnieks2Dana Kigitoviča3Andris Skride4Department of Internal Diseases, Riga Stradiņš University, LV-1079 Riga, LatviaDepartment of Internal Diseases, Riga Stradiņš University, LV-1079 Riga, LatviaDepartment of Internal Diseases, Riga Stradiņš University, LV-1079 Riga, LatviaDepartment of Internal Diseases, Riga Stradiņš University, LV-1079 Riga, LatviaDepartment of Internal Diseases, Riga Stradiņš University, LV-1079 Riga, Latvia<i>Background</i>: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and progressive condition; however, the true characteristics of CTEPH are still unknown, as notable regional variations exist in terms of patients’ age, baseline hemodynamic data, and management choices. This report aims to investigate the baseline clinical characteristics, incidence, and risk factors associated with CTEPH patients in Latvia from 2019 to 2020. <i>Methods</i>: The data were analyzed from a prospective, nationwide, Latvian pulmonary hypertension registry for incident CTEPH cases. The patients’ clinical characteristics were assessed at the time of diagnosis. <i>Results</i>: During the course of this study, a cohort of 13 patients with CTEPH were included for analysis. Among the enrolled CTEPH patients, most exhibited low exercise and functional capacity, with a median (±IQR) 6 min walk distance of 300.0 (±150.0) m. The median values (±IQR) for mean pulmonary artery pressure and pulmonary vascular resistance were 40.0 ± 13.0 mmHg and 7.35 ± 2.82 Wood units, respectively. The most common risk factors for CTEPH were a history of acute pulmonary embolism and a blood group other than O. <i>Conclusions</i>: The findings of this report revealed the characteristics of the Latvian CTEPH population, indicating that a significant proportion of patients are elderly individuals with multiple comorbidities.https://www.mdpi.com/1648-9144/59/8/1426chronic thromboembolic pulmonary hypertensionepidemiologyincidenceLatvianational registry |
| spellingShingle | Ričards Kauliņš Ainārs Rudzītis Aivars Lejnieks Dana Kigitoviča Andris Skride Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 Medicina chronic thromboembolic pulmonary hypertension epidemiology incidence Latvia national registry |
| title | Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 |
| title_full | Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 |
| title_fullStr | Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 |
| title_full_unstemmed | Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 |
| title_short | Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020 |
| title_sort | baseline clinical characteristics and incidence of chronic thromboembolic pulmonary hypertension patients in latvia 2019 2020 |
| topic | chronic thromboembolic pulmonary hypertension epidemiology incidence Latvia national registry |
| url | https://www.mdpi.com/1648-9144/59/8/1426 |
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