Cerebral hemodynamics in high-risk infants during the neonatal period
Objective. To estimate the impact of the complicated perinatal period on cerebral hemodynamics in high-risk neonates who have experienced hypoxia-ischemia and been born by caesarean section. Patients and methods. Structural characteristics of the brain and its hemodynamics were examined in 690 neona...
Main Authors: | , , , |
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Format: | Article |
Language: | Russian |
Published: |
Ltd. “The National Academy of Pediatric Science and Innovation”
2016-04-01
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Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
Subjects: | |
Online Access: | https://www.ped-perinatology.ru/jour/article/view/300 |
Summary: | Objective. To estimate the impact of the complicated perinatal period on cerebral hemodynamics in high-risk neonates who have experienced hypoxia-ischemia and been born by caesarean section. Patients and methods. Structural characteristics of the brain and its hemodynamics were examined in 690 neonates born by different modes of delivery at various gestational ages (out of them 540 neonates had experienced hypoxia-ischemia).Results. In the first 24 hours of life, the babies with a compromised perinatal period, especially after caesarean section, developed structural changes in the brain and its hemodynamic disorders that were correlated with the severity of prior hypoxia-ischemia and the degree of prematurity. The neonatal period was marked by the delayed recovery of cerebral hemodynamics in infants exposed to a set of damaging factors.Conclusion. The complicated perinatal period and the joint impact of hypoxia-ischemia, operative delivery, and preterm pregnancy on the fetus and the neonate result in persistent impairment of cerebral blood flow. The early diagnosis of brain structural and hemodynamic disorders serves as the basis for an in-depth examination of the central nervous system and for effective drug correction in order to prevent decompensation and its related complications. |
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ISSN: | 1027-4065 2500-2228 |