NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY
Backround: Celery (Apium graveolens L., Apiaceae) is one of the medicinal plants with secondary metabolite components that have pharmacological effects such as vitamin (choline) content. This study aims to evaluate the mechanism and interaction of choline contained in celery on its effectiveness as...
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| Format: | Article |
| Language: | English |
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Universitas Nahdlatul Ulama Surabaya
2021-09-01
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| Series: | Medical and Health Science Journal |
| Subjects: | |
| Online Access: | https://journal2.unusa.ac.id/index.php/MHSJ/article/view/2362 |
| _version_ | 1828451320313413632 |
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| author | Reza Mahendra Ainul Rofik Hotimah Masdan Salim Maria Ulfa Evy Silvia Awwaliyah |
| author_facet | Reza Mahendra Ainul Rofik Hotimah Masdan Salim Maria Ulfa Evy Silvia Awwaliyah |
| author_sort | Reza Mahendra |
| collection | DOAJ |
| description |
Backround: Celery (Apium graveolens L., Apiaceae) is one of the medicinal plants with secondary metabolite components that have pharmacological effects such as vitamin (choline) content. This study aims to evaluate the mechanism and interaction of choline contained in celery on its effectiveness as a neuroprotective.
Methods: This research is an experimental research using the in silico study.
Results: The insilico search found that the choline content in celery binds to Slc5a7, Chat and Ache. Which has a function in the process of neurotransmitter biosynthesis, neurotransmitter metabolic processes and neurotransmitter secretion processes
Conclusion: The celery (Apium graveolens L., Apiaceae) have pharmacological activity as neuroprotective through the interaction of Slc5a7, Chat and Ache
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| first_indexed | 2024-12-10T23:35:01Z |
| format | Article |
| id | doaj.art-d45706e3816d41759ec11f3917d68ae7 |
| institution | Directory Open Access Journal |
| issn | 2549-7588 2549-7596 |
| language | English |
| last_indexed | 2024-12-10T23:35:01Z |
| publishDate | 2021-09-01 |
| publisher | Universitas Nahdlatul Ulama Surabaya |
| record_format | Article |
| series | Medical and Health Science Journal |
| spelling | doaj.art-d45706e3816d41759ec11f3917d68ae72022-12-22T01:29:13ZengUniversitas Nahdlatul Ulama SurabayaMedical and Health Science Journal2549-75882549-75962021-09-015210.33086/mhsj.v5i2.2362NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDYReza Mahendra0Ainul Rofik1Hotimah Masdan Salim2Maria Ulfa3Evy Silvia Awwaliyah4Departemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Nahdlatul Ulama SurabayaDepartemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Nahdlatul Ulama SurabayaDepartemen Biokimia dan Ilmu Biomolekuler, Fakultas Kedokteran, Universitas Nahdlatul Ulama SurabayaDepartemen Dermatologi dan Kelamin Fakultas Kedokteran Universitas Nahdlatul Ulama SurabayaDepartemen Penyakit Dalam, Fakultas Kedokteran, Universitas Nahdlatul Ulama Surabaya Backround: Celery (Apium graveolens L., Apiaceae) is one of the medicinal plants with secondary metabolite components that have pharmacological effects such as vitamin (choline) content. This study aims to evaluate the mechanism and interaction of choline contained in celery on its effectiveness as a neuroprotective. Methods: This research is an experimental research using the in silico study. Results: The insilico search found that the choline content in celery binds to Slc5a7, Chat and Ache. Which has a function in the process of neurotransmitter biosynthesis, neurotransmitter metabolic processes and neurotransmitter secretion processes Conclusion: The celery (Apium graveolens L., Apiaceae) have pharmacological activity as neuroprotective through the interaction of Slc5a7, Chat and Ache https://journal2.unusa.ac.id/index.php/MHSJ/article/view/2362Celery (Apium graveolens)ColineInsilico |
| spellingShingle | Reza Mahendra Ainul Rofik Hotimah Masdan Salim Maria Ulfa Evy Silvia Awwaliyah NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY Medical and Health Science Journal Celery (Apium graveolens) Coline Insilico |
| title | NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY |
| title_full | NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY |
| title_fullStr | NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY |
| title_full_unstemmed | NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY |
| title_short | NEUROPROTECTIVE ACTIVITY OF EXTRACT OF CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY |
| title_sort | neuroprotective activity of extract of celery apium graveolens in insilico study |
| topic | Celery (Apium graveolens) Coline Insilico |
| url | https://journal2.unusa.ac.id/index.php/MHSJ/article/view/2362 |
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