Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study
BackgroundProgressive supranuclear palsy (PSP) is a parkinsonian-like progressive neurodegenerative syndrome. Key clinical features include ocular motor dysfunction, postural instability, and cognitive dysfunction. Maintaining and improving balance function and gait function are very important for p...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.955893/full |
| _version_ | 1798001037916766208 |
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| author | Naomi Matsuda Yasuyuki Takamatsu Ikuko Aiba |
| author_facet | Naomi Matsuda Yasuyuki Takamatsu Ikuko Aiba |
| author_sort | Naomi Matsuda |
| collection | DOAJ |
| description | BackgroundProgressive supranuclear palsy (PSP) is a parkinsonian-like progressive neurodegenerative syndrome. Key clinical features include ocular motor dysfunction, postural instability, and cognitive dysfunction. Maintaining and improving balance function and gait function are very important for patients with PSP with severe postural dysfunction and repeated falls. In addition, patients with PSP have a poor response to pharmacological treatment; hence, rehabilitation is a key approach in dealing with this syndrome. However, no conclusion on the beneficial effects of rehabilitation for patients with PSP have been established in the literature.ObjectivesThe effectiveness of multiple therapeutic exercise program with probable or possible PSP according to the Movement Disorder Society criteria for the clinical diagnosis of PSP was validated.MethodsParticipants underwent multiple therapeutic exercise program customized for each participant, including resistance training, balance training, and walking exercises that were performed for 60–80 minutes a day, 5 days a week for 4 weeks. The outcomes measured were as follows: pull test, Berg Balance Scale (BBS), timed up and go test (TUG), and gait speed test.ResultsA total of 117 patients with PSP were enrolled and the analysis was performed on 20 patients with probable PSP. Four-week rehabilitation significantly improved pull test (p = 0.034) and BBS scores (p = 0.001). There were no significant differences both TUG (p = 0.502) and gait speed (p = 0.813).ConclusionThe multiple therapeutic exercise program had beneficial effects on balance performance in patients with PSP in 4 weeks and could be an essential element in their rehabilitation. Although this pilot study was conducted without a control group, it provided valuable information for future prospective randomized controlled trials. |
| first_indexed | 2024-04-11T11:29:46Z |
| format | Article |
| id | doaj.art-d458c493c8284bf5ad00c0841ca6df92 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T11:29:46Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-d458c493c8284bf5ad00c0841ca6df922022-12-22T04:26:11ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-09-011310.3389/fneur.2022.955893955893Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot studyNaomi Matsuda0Yasuyuki Takamatsu1Ikuko Aiba2Department of Rehabilitation, National Hospital Organization Higashinagoya National Hospital, Nagoya, JapanDepartment of Rehabilitation Science, Faculty of Health Sciences, Hokkaido University, Sapporo, JapanDepartment of Neurology, National Hospital Organization Higashinagoya National Hospital, Nagoya, JapanBackgroundProgressive supranuclear palsy (PSP) is a parkinsonian-like progressive neurodegenerative syndrome. Key clinical features include ocular motor dysfunction, postural instability, and cognitive dysfunction. Maintaining and improving balance function and gait function are very important for patients with PSP with severe postural dysfunction and repeated falls. In addition, patients with PSP have a poor response to pharmacological treatment; hence, rehabilitation is a key approach in dealing with this syndrome. However, no conclusion on the beneficial effects of rehabilitation for patients with PSP have been established in the literature.ObjectivesThe effectiveness of multiple therapeutic exercise program with probable or possible PSP according to the Movement Disorder Society criteria for the clinical diagnosis of PSP was validated.MethodsParticipants underwent multiple therapeutic exercise program customized for each participant, including resistance training, balance training, and walking exercises that were performed for 60–80 minutes a day, 5 days a week for 4 weeks. The outcomes measured were as follows: pull test, Berg Balance Scale (BBS), timed up and go test (TUG), and gait speed test.ResultsA total of 117 patients with PSP were enrolled and the analysis was performed on 20 patients with probable PSP. Four-week rehabilitation significantly improved pull test (p = 0.034) and BBS scores (p = 0.001). There were no significant differences both TUG (p = 0.502) and gait speed (p = 0.813).ConclusionThe multiple therapeutic exercise program had beneficial effects on balance performance in patients with PSP in 4 weeks and could be an essential element in their rehabilitation. Although this pilot study was conducted without a control group, it provided valuable information for future prospective randomized controlled trials.https://www.frontiersin.org/articles/10.3389/fneur.2022.955893/fullprogressive supranuclear palsyexerciserehabilitationrehabilitation researchbalance |
| spellingShingle | Naomi Matsuda Yasuyuki Takamatsu Ikuko Aiba Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study Frontiers in Neurology progressive supranuclear palsy exercise rehabilitation rehabilitation research balance |
| title | Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study |
| title_full | Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study |
| title_fullStr | Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study |
| title_full_unstemmed | Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study |
| title_short | Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: A pilot study |
| title_sort | effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy a pilot study |
| topic | progressive supranuclear palsy exercise rehabilitation rehabilitation research balance |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.955893/full |
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