mRNA, lncRNA, and circRNA expression profiles in a new aortic dissection murine model induced by hypoxia and Ang II

mRNA, lncRNA, and circRNA expression profiles in a new aortic dissection murine model induced by hypoxia and Ang II

Background and aimsAortic dissection (AD) is a cardiovascular emergency with degeneration of the aortic media. Mounting evidence indicates obstructive sleep apnea (OSA) as an independent risk factor for AD development with unknown mechanisms. This study aims to establish a stable murine model of OSA...

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Bibliographic Details
Main Authors: Yuanyuan Li, Xiaozhu Ma, Shuai Mei, Yueping Ji, Dong Wang, Liqun He, Dating Sun, Jiangtao Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic dissection
obstructive sleep apnea
hypoxia
bioinformatics
aortic structure
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.984087/full

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