Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent
During the last few decades, many studies have focused on the development of environmentally friendly, efficient, and miniaturized sample preparation methods. In this study, solid-phase microextraction and electromembrane extraction methods were integrated to take advantage of both methods and achie...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Engineering Proceedings |
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| Online Access: | https://www.mdpi.com/2673-4591/35/1/36 |
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| author | Razieh Zamani Yadollah Yamini |
| author_facet | Razieh Zamani Yadollah Yamini |
| author_sort | Razieh Zamani |
| collection | DOAJ |
| description | During the last few decades, many studies have focused on the development of environmentally friendly, efficient, and miniaturized sample preparation methods. In this study, solid-phase microextraction and electromembrane extraction methods were integrated to take advantage of both methods and achieve higher extraction recoveries and clean-up. In this regard, Cu/Cr layered double hydroxide was dispersed in a poly(methacrylic acid-co-ethylene glycol dimethacrylate) polymerization mixture, and in situ polymerization was performed in the acceptor phase channel. Thereafter, EME-SPME on a chip was developed to extract non-steroidal anti-inflammatory drugs. The obtained limits of detection were 0.1–0.25 ng mL<sup>−1</sup>. Under evaluation of this method, extraction recoveries were obtained in the range of 83.34–90.87%, which corresponded to preconcentration factors of 56–61. The method was applied for the extraction of the drugs from real samples such as breast milk, urine, and plasma, and satisfactory results were obtained. |
| first_indexed | 2024-03-10T22:48:40Z |
| format | Article |
| id | doaj.art-d46237067fc84cfa9ce8dee1e3f449c7 |
| institution | Directory Open Access Journal |
| issn | 2673-4591 |
| language | English |
| last_indexed | 2024-03-10T22:48:40Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Engineering Proceedings |
| spelling | doaj.art-d46237067fc84cfa9ce8dee1e3f449c72023-11-19T10:32:23ZengMDPI AGEngineering Proceedings2673-45912023-05-013513610.3390/IECB2023-14705Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the SorbentRazieh Zamani0Yadollah Yamini1Department of Chemistry, Tarbiat Modares University, Tehran 14115-175, IranDepartment of Chemistry, Tarbiat Modares University, Tehran 14115-175, IranDuring the last few decades, many studies have focused on the development of environmentally friendly, efficient, and miniaturized sample preparation methods. In this study, solid-phase microextraction and electromembrane extraction methods were integrated to take advantage of both methods and achieve higher extraction recoveries and clean-up. In this regard, Cu/Cr layered double hydroxide was dispersed in a poly(methacrylic acid-co-ethylene glycol dimethacrylate) polymerization mixture, and in situ polymerization was performed in the acceptor phase channel. Thereafter, EME-SPME on a chip was developed to extract non-steroidal anti-inflammatory drugs. The obtained limits of detection were 0.1–0.25 ng mL<sup>−1</sup>. Under evaluation of this method, extraction recoveries were obtained in the range of 83.34–90.87%, which corresponded to preconcentration factors of 56–61. The method was applied for the extraction of the drugs from real samples such as breast milk, urine, and plasma, and satisfactory results were obtained.https://www.mdpi.com/2673-4591/35/1/36electromembrane extractionon-chipmicrofluidicsnon-steroidal anti-inflammatory drugsbreast milk |
| spellingShingle | Razieh Zamani Yadollah Yamini Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent Engineering Proceedings electromembrane extraction on-chip microfluidics non-steroidal anti-inflammatory drugs breast milk |
| title | Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent |
| title_full | Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent |
| title_fullStr | Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent |
| title_full_unstemmed | Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent |
| title_short | Combination of On-Chip Electromembrane Extraction with Solid-Phase Microextraction Using a Monolithic Nanocomposite as the Sorbent |
| title_sort | combination of on chip electromembrane extraction with solid phase microextraction using a monolithic nanocomposite as the sorbent |
| topic | electromembrane extraction on-chip microfluidics non-steroidal anti-inflammatory drugs breast milk |
| url | https://www.mdpi.com/2673-4591/35/1/36 |
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