Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital
Aim: To evaluate an immunochromatographic assay method in the serodiagnosis of tuberculosis. Patients and Methods: Thirty participants, 25 patients and five normal individuals were studied between July and October 2001. 40μL, of whole blood or 20μL of serum was used in the test for each kit. Using...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2004-01-01
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| Series: | International Journal of Medicine and Health Development |
| Subjects: | |
| Online Access: | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2004;volume=9;issue=1;spage=42;epage=44;aulast=Ohanu;type=0 |
| _version_ | 1798018692251910144 |
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| author | Martin E Ohanu P O Okonkwo Margaret Aghaji N Njeze A Nwokocha E Ele |
| author_facet | Martin E Ohanu P O Okonkwo Margaret Aghaji N Njeze A Nwokocha E Ele |
| author_sort | Martin E Ohanu |
| collection | DOAJ |
| description | Aim: To evaluate an immunochromatographic assay method in the serodiagnosis of tuberculosis.
Patients and Methods: Thirty participants, 25 patients and five normal individuals were studied between July and October 2001. 40μL, of whole blood or 20μL of serum was used in the test for each kit. Using sputum smear microscopy as gold standard, the new method was compared with x-ray diagnosis
Results: The sensitivity, specificity and efficiency of the new immunodiagnostic method were 89.5%, 77.7% and 85.7% while that of X-ray were 75%, 50% and 66.6% respectively.
Conclusion: The new immunodiagnostic method gave better results in sensitivity, specificity (as well as in other performance indices) than X-ray diagnosis. The new test is rapid, reliable and field operable. |
| first_indexed | 2024-04-11T16:27:22Z |
| format | Article |
| id | doaj.art-d462408151544566aa62df1c554611dd |
| institution | Directory Open Access Journal |
| issn | 2635-3695 |
| language | English |
| last_indexed | 2024-04-11T16:27:22Z |
| publishDate | 2004-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Medicine and Health Development |
| spelling | doaj.art-d462408151544566aa62df1c554611dd2022-12-22T04:14:07ZengWolters Kluwer Medknow PublicationsInternational Journal of Medicine and Health Development2635-36952004-01-01914244Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospitalMartin E OhanuP O OkonkwoMargaret AghajiN NjezeA NwokochaE EleAim: To evaluate an immunochromatographic assay method in the serodiagnosis of tuberculosis. Patients and Methods: Thirty participants, 25 patients and five normal individuals were studied between July and October 2001. 40μL, of whole blood or 20μL of serum was used in the test for each kit. Using sputum smear microscopy as gold standard, the new method was compared with x-ray diagnosis Results: The sensitivity, specificity and efficiency of the new immunodiagnostic method were 89.5%, 77.7% and 85.7% while that of X-ray were 75%, 50% and 66.6% respectively. Conclusion: The new immunodiagnostic method gave better results in sensitivity, specificity (as well as in other performance indices) than X-ray diagnosis. The new test is rapid, reliable and field operable.http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2004;volume=9;issue=1;spage=42;epage=44;aulast=Ohanu;type=0tuberculosisnigeriaimmunodiagnosis |
| spellingShingle | Martin E Ohanu P O Okonkwo Margaret Aghaji N Njeze A Nwokocha E Ele Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital International Journal of Medicine and Health Development tuberculosis nigeria immunodiagnosis |
| title | Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital |
| title_full | Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital |
| title_fullStr | Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital |
| title_full_unstemmed | Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital |
| title_short | Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital |
| title_sort | diagnosis of tuberculosis experience with use of an immunochromatographic assay in a nigerian hospital |
| topic | tuberculosis nigeria immunodiagnosis |
| url | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2004;volume=9;issue=1;spage=42;epage=44;aulast=Ohanu;type=0 |
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