ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase

ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase

Abstract Background Mannose, a natural hexose existing in daily food, has been demonstrated to preferentially inhibit the progression of tumors with low expression of phosphate mannose isomerase (PMI). However, its function in thyroid cancer still remains elusive. Methods MTT, colony formation and f...

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Bibliographic Details
Main Authors: Sharui Ma, Na Wang, Rui Liu, Rui Zhang, Hui Dang, Yubo Wang, Simeng Wang, Zekun Zeng, Meiju Ji, Peng Hou
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Thyroid cancer
Mannose
Phosphate mannose isomerase (PMI)
ZIP10
Cellular glycolysis
Online Access:https://doi.org/10.1186/s13046-021-02195-z

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