Advancing CAR-based immunotherapies in solid tumors: CAR- macrophages and neutrophils

Advancing CAR-based immunotherapies in solid tumors: CAR- macrophages and neutrophils

Macrophages and neutrophils are the main components of the innate immune system and play important roles in promoting angiogenesis, extracellular matrix remodeling, cancer cell proliferation, and metastasis in the tumor microenvironment (TME). They can also be harnessed to mediate cytotoxic tumor ki...

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Bibliographic Details
Main Authors: Yanling Liang, Qumiao Xu, Qianqian Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
CAR macrophages
CAR neutrophils
solid tumor
cancer immunotherapy
adoptive cell therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291619/full

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