Field testing of recombinant subunit vaccines against Teladorsagia circumcincta in lambing ewes demonstrates a lack of efficacy in the face of a multi-species parasite challenge

Field testing of recombinant subunit vaccines against Teladorsagia circumcincta in lambing ewes demonstrates a lack of efficacy in the face of a multi-species parasite challenge

IntroductionWe previously demonstrated efficacy of an 8-antigen recombinant subunit vaccine against a single species homologous Teladorsagia circumcincta challenge in lambs and in lambing ewes in pen trials. We subsequently demonstrated efficacy of a simplified, 2-antigen, version of this vaccine in...

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Bibliographic Details
Main Authors: Alasdair J. Nisbet, Tom N. McNeilly, Daniel R. G. Price, Yvonne Bartley, Margaret Oliver, Dave McBean, Leigh Andrews, Gillian Mitchell, Rachael Duncan, Sarah Brocklehurst, Fiona Kenyon
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Parasitology
Subjects:
parasitic gastroenteritis
nematode vaccine
teladorsagiasis
field trial
recombinant
Online Access:https://www.frontiersin.org/articles/10.3389/fpara.2024.1360029/full

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