Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs)

There are various methods to synthesize superparamagnetic nanoparticles (SPIONs) useful for MPI (magnetic particle imaging) and in therapy (Hypothermia) such as co-precipitation, hydrothermal reactions etc. In this research, the focus is to analyse the effects of crucial parameters such as effect of...

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Bibliographic Details
Main Authors: Malhotra Ankit, Spieß Felix, Stegelmeier Corinna, Debbeler Christina, Lüdtke-Buzug Kerstin
Format: Article
Language:English
Published: De Gruyter 2016-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2016-0117
Description
Summary:There are various methods to synthesize superparamagnetic nanoparticles (SPIONs) useful for MPI (magnetic particle imaging) and in therapy (Hypothermia) such as co-precipitation, hydrothermal reactions etc. In this research, the focus is to analyse the effects of crucial parameters such as effect of molecular mass of dextran and temperature of the co-precipitation. These parameters play a crucial role in the inherent magnetic properties of the resulting SPIONs. The amplitude spectrum and hysteresis curve of the SPIONs is analysed with MPS (magnetic particle spectrometer). PCCS (photon cross-correlation spectroscopy) measurements are done to analyse the size distribution of hydrodynamic diameter the resulting SPIONs.
ISSN:2364-5504