O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiology of depression. However, the molecular mechanis...

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Main Authors:	Jun Fan, Fang Guo, Ran Mo, Liang-Yu Chen, Jia-Wen Mo, Cheng-Lin Lu, Jing Ren, Qiu-Ling Zhong, Xiao-Jing Kuang, You-Lu Wen, Ting-Ting Gu, Jin-Ming Liu, Shu-Ji Li, Ying-Ying Fang, Cunyou Zhao, Tian-Ming Gao, Xiong Cao
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2023-04-01
Series:	The Journal of Clinical Investigation
Subjects:	Neuroscience
Online Access:	https://doi.org/10.1172/JCI160016

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