Hearing Loss in Acromegaly - A Review

Abstract Introduction Acromegaly is a chronic disease caused by growth hormone (GH) excess due to a GH-secreting pituitary adenoma in most cases. There is reasonable data to presume the possible influence of chronic GH and insulin-like growth factor I (IGF-I) hyperproduction on the anat...

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Bibliographic Details
Main Authors: Liane Sousa Teixeira, Isabelle Braz de Oliveira Silva, Andre Luiz Lopes Sampaio, Carlos Augusto Pires de Oliveira, Fayez Bahamad Júnior
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2017-06-01
Series:International Archives of Otorhinolaryngology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1603619
Description
Summary:Abstract Introduction Acromegaly is a chronic disease caused by growth hormone (GH) excess due to a GH-secreting pituitary adenoma in most cases. There is reasonable data to presume the possible influence of chronic GH and insulin-like growth factor I (IGF-I) hyperproduction on the anatomical structures involved in normal sound perception, and on its conductive and/or sensorineural part. Objectives To review the literature about acromegaly and hearing loss. Data Synthesis A systematic literature search was performed using the MEDLINE database, including hand-searching reference lists from original articles. The search was performed using the terms hearing loss and acromegaly, and only 5 studies were found. Conclusion The results are not consistent, but led to different conclusions. Therefore, more studies with greater numbers of patients with acromegaly are needed.
ISSN:1809-9777
1809-4864