A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up aga...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2022-09-01
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Series: | Geriatric Care |
Subjects: | |
Online Access: | https://www.pagepressjournals.org/index.php/gc/article/view/10668 |
Summary: | Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up against a whole series of critical points that may favor its misdiagnosis. The aim of our article is to discuss the most relevant of them: the frequent occurrence of a seronegative subset, the presence of systemic features not related to sicca syndrome, the sicca syndrome as iatrogenic manifestation and the possibility of a biopsy false negative of labial salivary glands.
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ISSN: | 2465-1109 2465-1397 |