A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up aga...

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Main Authors: Ciro Manzo, Alberto Castagna, Giovanni Ruotolo
Format: Article
Language:English
Published: PAGEPress Publications 2022-09-01
Series:Geriatric Care
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/gc/article/view/10668
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author Ciro Manzo
Alberto Castagna
Giovanni Ruotolo
author_facet Ciro Manzo
Alberto Castagna
Giovanni Ruotolo
author_sort Ciro Manzo
collection DOAJ
description Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up against a whole series of critical points that may favor its misdiagnosis. The aim of our article is to discuss the most relevant of them: the frequent occurrence of a seronegative subset, the presence of systemic features not related to sicca syndrome, the sicca syndrome as iatrogenic manifestation and the possibility of a biopsy false negative of labial salivary glands.
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spelling doaj.art-d470db5442a8442bb2066c82f5a7a25c2022-12-22T04:26:59ZengPAGEPress PublicationsGeriatric Care2465-11092465-13972022-09-018210.4081/gc.2022.10668A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatricianCiro Manzo0Alberto Castagna1Giovanni Ruotolo2Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic, Health District no. 59, Azienda Sanitaria Locale Napoli 3 SudPrimary Care Department, Health District of Soverato, Azienda Sanitaria Provinciale CatanzaroGeriatric Medicine Department, Azienda Ospedaliera ‘Pugliese-Ciaccio’, Catanzaro Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease where xerophthalmia, xerostomia and presence of anti-SSA and anti-SSB antibodies are typical features. Its prevalence is higher in over-65 aged population than in other age groups. In the elderly, pSS diagnosis comes up against a whole series of critical points that may favor its misdiagnosis. The aim of our article is to discuss the most relevant of them: the frequent occurrence of a seronegative subset, the presence of systemic features not related to sicca syndrome, the sicca syndrome as iatrogenic manifestation and the possibility of a biopsy false negative of labial salivary glands. https://www.pagepressjournals.org/index.php/gc/article/view/10668Elderly-onset Sjögren’s syndromesicca syndromediagnostic and classification criteriaseronegative subset of diseaselabial salivary glands biopsy.
spellingShingle Ciro Manzo
Alberto Castagna
Giovanni Ruotolo
A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
Geriatric Care
Elderly-onset Sjögren’s syndrome
sicca syndrome
diagnostic and classification criteria
seronegative subset of disease
labial salivary glands biopsy.
title A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
title_full A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
title_fullStr A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
title_full_unstemmed A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
title_short A journey inside the elderly-onset primary Sjögren’s syndrome, looking for useful tips for the geriatrician
title_sort journey inside the elderly onset primary sjogren s syndrome looking for useful tips for the geriatrician
topic Elderly-onset Sjögren’s syndrome
sicca syndrome
diagnostic and classification criteria
seronegative subset of disease
labial salivary glands biopsy.
url https://www.pagepressjournals.org/index.php/gc/article/view/10668
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