Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
Abstract The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-06-01
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| Series: | MicrobiologyOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/mbo3.1303 |
| _version_ | 1818218531323379712 |
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| author | Hokuto Ohtsuka Kazuki Imada Takafumi Shimasaki Hirofumi Aiba |
| author_facet | Hokuto Ohtsuka Kazuki Imada Takafumi Shimasaki Hirofumi Aiba |
| author_sort | Hokuto Ohtsuka |
| collection | DOAJ |
| description | Abstract The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the presence of a cell of the opposite sex, the cells undergo fusion through conjugation and sporulation through meiosis. S. pombe spores are highly resistant to diverse stresses and may survive for a very long time. In this minireview, among the various sexual differentiation processes induced by starvation, we focused on and summarized the findings of the molecular mechanisms of spore formation in fission yeast. Furthermore, comparative measurements of the chronological lifespan of stationary phase cells and G0 cells and the survival period of spore cells revealed that the spore cells survived for a long period, indicating the presence of an effective mechanism for survival. Currently, many molecules involved in sporulation and their functions are being discovered; however, our understanding of these is not complete. Further understanding of spores may not only deepen our comprehension of sexual differentiation but may also provide hints for sustaining life. |
| first_indexed | 2024-12-12T07:25:14Z |
| format | Article |
| id | doaj.art-d4711eea1b1a4384ad241d30083a76c5 |
| institution | Directory Open Access Journal |
| issn | 2045-8827 |
| language | English |
| last_indexed | 2024-12-12T07:25:14Z |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | MicrobiologyOpen |
| spelling | doaj.art-d4711eea1b1a4384ad241d30083a76c52022-12-22T00:33:10ZengWileyMicrobiologyOpen2045-88272022-06-01113n/an/a10.1002/mbo3.1303Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombeHokuto Ohtsuka0Kazuki Imada1Takafumi Shimasaki2Hirofumi Aiba3Laboratory of Molecular Microbiology, Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences Nagoya University Chikusa‐ku Nagoya JapanDepartment of Chemistry and Biochemistry National Institute of Technology (KOSEN), Suzuka College Suzuka JapanLaboratory of Molecular Microbiology, Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences Nagoya University Chikusa‐ku Nagoya JapanLaboratory of Molecular Microbiology, Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences Nagoya University Chikusa‐ku Nagoya JapanAbstract The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the presence of a cell of the opposite sex, the cells undergo fusion through conjugation and sporulation through meiosis. S. pombe spores are highly resistant to diverse stresses and may survive for a very long time. In this minireview, among the various sexual differentiation processes induced by starvation, we focused on and summarized the findings of the molecular mechanisms of spore formation in fission yeast. Furthermore, comparative measurements of the chronological lifespan of stationary phase cells and G0 cells and the survival period of spore cells revealed that the spore cells survived for a long period, indicating the presence of an effective mechanism for survival. Currently, many molecules involved in sporulation and their functions are being discovered; however, our understanding of these is not complete. Further understanding of spores may not only deepen our comprehension of sexual differentiation but may also provide hints for sustaining life.https://doi.org/10.1002/mbo3.1303fission yeastlifespanSchizosaccharomyces pombesexual differentiationsporestarvation |
| spellingShingle | Hokuto Ohtsuka Kazuki Imada Takafumi Shimasaki Hirofumi Aiba Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe MicrobiologyOpen fission yeast lifespan Schizosaccharomyces pombe sexual differentiation spore starvation |
| title | Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe |
| title_full | Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe |
| title_fullStr | Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe |
| title_full_unstemmed | Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe |
| title_short | Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe |
| title_sort | sporulation a response to starvation in the fission yeast schizosaccharomyces pombe |
| topic | fission yeast lifespan Schizosaccharomyces pombe sexual differentiation spore starvation |
| url | https://doi.org/10.1002/mbo3.1303 |
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