sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases
Abstract Objective Stereoelectroencephalography (sEEG) is an intracranial encephalography method of expanding use. The need for increased epilepsy surgery access has led to the consideration of sEEG adoption by new or expanding surgical epilepsy programs. Data regarding safety and efficacy are uncom...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-12-01
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| Series: | Epilepsia Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/epi4.12535 |
| _version_ | 1818404988174467072 |
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| author | Christopher Miller Bryan Schatmeyer Patrick Landazuri Utku Uysal Jules Nazzaro Michael J. Kinsman Paul J. Camarata Carol M. Ulloa Nancy Hammond Caleb Pearson Vishal Shah Jennifer J. Cheng |
| author_facet | Christopher Miller Bryan Schatmeyer Patrick Landazuri Utku Uysal Jules Nazzaro Michael J. Kinsman Paul J. Camarata Carol M. Ulloa Nancy Hammond Caleb Pearson Vishal Shah Jennifer J. Cheng |
| author_sort | Christopher Miller |
| collection | DOAJ |
| description | Abstract Objective Stereoelectroencephalography (sEEG) is an intracranial encephalography method of expanding use. The need for increased epilepsy surgery access has led to the consideration of sEEG adoption by new or expanding surgical epilepsy programs. Data regarding safety and efficacy are uncommon outside of high‐volume, well‐established centers, which may be less applicable to newer or low‐volume centers. The objective of this study was to add to the sEEG outcomes in the literature from the perspective of a rapidly expanding center. Methods A retrospective chart review of consecutive sEEG cases from January 2016 to December 2019 was performed. Data extraction included demographic data, surgical data, and outcome data, which pertinently examined surgical method, progression to therapeutic procedure, clinically significant adverse events, and Engel outcomes. Results One hundred and fifty‐two sEEG procedures were performed on 131 patients. Procedures averaged 10.5 electrodes for a total of 1603 electrodes. The majority (84%) of patients progressed to a therapeutic procedure. Six clinically significant complications occurred: three retained electrodes, two hemorrhages, and one failure to complete investigation. Only one complication resulted in a permanent deficit. Engel 1 outcome was achieved in 63.3% of patients reaching one‐year follow‐up after a curative procedure. Significance New or expanding epilepsy surgery centers can appropriately consider the use of sEEG. The complication rate is low and the majority of patients progress to therapeutic surgery. Procedural safety, progression to therapeutic intervention, and Engel outcomes are comparable to cohorts from long‐established epilepsy surgery programs. |
| first_indexed | 2024-12-14T08:48:54Z |
| format | Article |
| id | doaj.art-d471aa5c46904b6f8af629bd76816979 |
| institution | Directory Open Access Journal |
| issn | 2470-9239 |
| language | English |
| last_indexed | 2024-12-14T08:48:54Z |
| publishDate | 2021-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Epilepsia Open |
| spelling | doaj.art-d471aa5c46904b6f8af629bd768169792022-12-21T23:09:06ZengWileyEpilepsia Open2470-92392021-12-016469470210.1002/epi4.12535sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive casesChristopher Miller0Bryan Schatmeyer1Patrick Landazuri2Utku Uysal3Jules Nazzaro4Michael J. Kinsman5Paul J. Camarata6Carol M. Ulloa7Nancy Hammond8Caleb Pearson9Vishal Shah10Jennifer J. Cheng11Department of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurology The University of Kansas School of Medicine Kansas City Kansas USADepartment of Neurosurgery The University of Kansas School of Medicine Kansas City Kansas USAAbstract Objective Stereoelectroencephalography (sEEG) is an intracranial encephalography method of expanding use. The need for increased epilepsy surgery access has led to the consideration of sEEG adoption by new or expanding surgical epilepsy programs. Data regarding safety and efficacy are uncommon outside of high‐volume, well‐established centers, which may be less applicable to newer or low‐volume centers. The objective of this study was to add to the sEEG outcomes in the literature from the perspective of a rapidly expanding center. Methods A retrospective chart review of consecutive sEEG cases from January 2016 to December 2019 was performed. Data extraction included demographic data, surgical data, and outcome data, which pertinently examined surgical method, progression to therapeutic procedure, clinically significant adverse events, and Engel outcomes. Results One hundred and fifty‐two sEEG procedures were performed on 131 patients. Procedures averaged 10.5 electrodes for a total of 1603 electrodes. The majority (84%) of patients progressed to a therapeutic procedure. Six clinically significant complications occurred: three retained electrodes, two hemorrhages, and one failure to complete investigation. Only one complication resulted in a permanent deficit. Engel 1 outcome was achieved in 63.3% of patients reaching one‐year follow‐up after a curative procedure. Significance New or expanding epilepsy surgery centers can appropriately consider the use of sEEG. The complication rate is low and the majority of patients progress to therapeutic surgery. Procedural safety, progression to therapeutic intervention, and Engel outcomes are comparable to cohorts from long‐established epilepsy surgery programs.https://doi.org/10.1002/epi4.12535invasive encephalographysEEGstereoelectroencephalographysurgical epilepsy |
| spellingShingle | Christopher Miller Bryan Schatmeyer Patrick Landazuri Utku Uysal Jules Nazzaro Michael J. Kinsman Paul J. Camarata Carol M. Ulloa Nancy Hammond Caleb Pearson Vishal Shah Jennifer J. Cheng sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases Epilepsia Open invasive encephalography sEEG stereoelectroencephalography surgical epilepsy |
| title | sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases |
| title_full | sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases |
| title_fullStr | sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases |
| title_full_unstemmed | sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases |
| title_short | sEEG for expansion of a surgical epilepsy program: Safety and efficacy in 152 consecutive cases |
| title_sort | seeg for expansion of a surgical epilepsy program safety and efficacy in 152 consecutive cases |
| topic | invasive encephalography sEEG stereoelectroencephalography surgical epilepsy |
| url | https://doi.org/10.1002/epi4.12535 |
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