Symposium 13: Prediabetes and brain
Prediabetes is a serious but reversible problem characterized by hyperglycemia and insulin resistance1. Decline in β-cell function was seen in prediabetes due to metabolic and epigenetic changes and alterations at the level of its cellular biology (including transdifferentiation, endoplasmic reticul...
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| Format: | Article |
| Language: | Spanish |
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Sello Editorial Lugones
2022-09-01
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| Series: | Revista de la Sociedad Argentina de Diabetes |
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| Online Access: | https://revistasad.com/index.php/diabetes/article/view/623 |
| _version_ | 1811309208737415168 |
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| author | Gustavo Díaz |
| author_facet | Gustavo Díaz |
| author_sort | Gustavo Díaz |
| collection | DOAJ |
| description | Prediabetes is a serious but reversible problem characterized by hyperglycemia and insulin resistance1. Decline in β-cell function was seen in prediabetes due to metabolic and epigenetic changes and alterations at the level of its cellular biology (including transdifferentiation, endoplasmic reticulum stress, autophagy, and apoptosis), which leads to decreased availability of insulin and insulin-like growth factors in the system central nervous system, which regulate brain neuroplasticity and neurogenesis2. patients with prediabetes showed lower performance in neurocognitive tests and this has been associated with the onset of cognitive impairment1.
Cognitive impairment begins with subtle, slow and progressive cognitive declines, more severe in older adults (AM) (≥65 years). This state of decline and loss of function Higher mental health is not an inevitable consequence of getting older. Many nonagenarians and centenarians have their cognitive functions preserved and in the “Study of autopsies of people age 90+ based on US population.” Almost half of the people with dementia did not have sufficient neuropathological evidence to explain their cognitive symptoms3. |
| first_indexed | 2024-04-13T09:38:13Z |
| format | Article |
| id | doaj.art-d4746e16e21c401cbacabeaae538124f |
| institution | Directory Open Access Journal |
| issn | 0325-5247 2346-9420 |
| language | Spanish |
| last_indexed | 2024-04-13T09:38:13Z |
| publishDate | 2022-09-01 |
| publisher | Sello Editorial Lugones |
| record_format | Article |
| series | Revista de la Sociedad Argentina de Diabetes |
| spelling | doaj.art-d4746e16e21c401cbacabeaae538124f2022-12-22T02:52:02ZspaSello Editorial LugonesRevista de la Sociedad Argentina de Diabetes0325-52472346-94202022-09-01563Sup848410.47196/diab.v56i3Sup.623537Symposium 13: Prediabetes and brainGustavo Díaz0Médico cirujano, especialista en Diabetes, Universidad Nacional de Córdoba, Córdoba, ArgentinaPrediabetes is a serious but reversible problem characterized by hyperglycemia and insulin resistance1. Decline in β-cell function was seen in prediabetes due to metabolic and epigenetic changes and alterations at the level of its cellular biology (including transdifferentiation, endoplasmic reticulum stress, autophagy, and apoptosis), which leads to decreased availability of insulin and insulin-like growth factors in the system central nervous system, which regulate brain neuroplasticity and neurogenesis2. patients with prediabetes showed lower performance in neurocognitive tests and this has been associated with the onset of cognitive impairment1. Cognitive impairment begins with subtle, slow and progressive cognitive declines, more severe in older adults (AM) (≥65 years). This state of decline and loss of function Higher mental health is not an inevitable consequence of getting older. Many nonagenarians and centenarians have their cognitive functions preserved and in the “Study of autopsies of people age 90+ based on US population.” Almost half of the people with dementia did not have sufficient neuropathological evidence to explain their cognitive symptoms3.https://revistasad.com/index.php/diabetes/article/view/623prediabetesdeterioro cognitivo |
| spellingShingle | Gustavo Díaz Symposium 13: Prediabetes and brain Revista de la Sociedad Argentina de Diabetes prediabetes deterioro cognitivo |
| title | Symposium 13: Prediabetes and brain |
| title_full | Symposium 13: Prediabetes and brain |
| title_fullStr | Symposium 13: Prediabetes and brain |
| title_full_unstemmed | Symposium 13: Prediabetes and brain |
| title_short | Symposium 13: Prediabetes and brain |
| title_sort | symposium 13 prediabetes and brain |
| topic | prediabetes deterioro cognitivo |
| url | https://revistasad.com/index.php/diabetes/article/view/623 |
| work_keys_str_mv | AT gustavodiaz symposium13prediabetesandbrain |