Sex-dependent effects of long-term clozapine or haloperidol medication on red blood cells and liver iron metabolism in Sprague Dawley rats as a model of metabolic syndrome

Sex-dependent effects of long-term clozapine or haloperidol medication on red blood cells and liver iron metabolism in Sprague Dawley rats as a model of metabolic syndrome

Abstract Background Patients with liver diseases often have some form of anemia. Hematological dyscrasias are known side effects of antipsychotic drug medication and the occurrence of agranulocytosis under clozapine is well described. However, the sex-dependent impact of clozapine and haloperidol on...

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Bibliographic Details
Main Authors: Marie-Luise Bouvier, Karin Fehsel, Andrea Schmitt, Eva Meisenzahl-Lechner, Wolfgang Gaebel, Martina von Wilmsdorff
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Clozapine
Haloperidol
Blood dyscrasia
Hepatic iron metabolism
Online Access:https://doi.org/10.1186/s40360-021-00544-4

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