Antiparasitic activity of FLLL-32 against four Babesia species, B. bovis, B. bigemina, B. divergens and B. caballi, and one Theileria species, Theileria equi in vitro, and Babesia microti in mice

Antiparasitic activity of FLLL-32 against four Babesia species, B. bovis, B. bigemina, B. divergens and B. caballi, and one Theileria species, Theileria equi in vitro, and Babesia microti in mice

Introduction: FLLL-32, a synthetic analog of curcumin, is a potent inhibitor of STAT3’s constitutive activation in a variety of cancer cells, and its anticancer properties have been demonstrated both in vitro and in vivo. It is also suggested that it might have other pharmacological activities inclu...

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Main Authors: Shimaa Abd El-Salam El-Sayed, El-Sayed El-Alfy, Hanadi B. Baghdadi, Mohamed Z. Sayed-Ahmed, Saad S. Alqahtani, Nawazish Alam, Sarfaraz Ahmad, Md. Sajid Ali, Ikuo Igarashi, Mohamed Abdo Rizk
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
FLLL-32
Babesia
Theileria equi
in vitro
in vivo
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1278451/full

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