The structural basis of promiscuity in small multidrug resistance transporters
Gdx-Clo is a bacterial transporter from the small multidrug resistance (SMR) family. Here, the authors use solid supported membrane electrophysiology to characterize Gdx-Clo functionally and report crystal structures of Gdx-Clo which confirm the dual topology architecture and offer insight into subs...
Main Authors: | Ali A. Kermani, Christian B. Macdonald, Olive E. Burata, B. Ben Koff, Akiko Koide, Eric Denbaum, Shohei Koide, Randy B. Stockbridge |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19820-8 |
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