A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis
Background: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal malignancy with very aggressive biology and increasing incidence. Ovarian metastasis is an exceptionally rare site for MCC, and only two cases have been reported in the literature. Case Report: We report MCC with ovarian metastas...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2014-12-01
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| Series: | Balkan Medical Journal |
| Subjects: | |
| Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=277 |
| _version_ | 1797922002991841280 |
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| author | Arbil Açıkalın Aysun Uğuz Derya Gümürdülü Semra Paydaş Ümran Küçükgöz Güleç |
| author_facet | Arbil Açıkalın Aysun Uğuz Derya Gümürdülü Semra Paydaş Ümran Küçükgöz Güleç |
| author_sort | Arbil Açıkalın |
| collection | DOAJ |
| description | Background: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal malignancy with very aggressive biology and increasing incidence. Ovarian metastasis is an exceptionally rare site for MCC, and only two cases have been reported in the literature.
Case Report: We report MCC with ovarian metastasis. A 34 year-old female with previously excised MCC from preauricular skin presented with a pelvic mass 15 months after first diagnosis. Anti-cytokeratin (CK) 20 positivity, LCA (leucocyte common antigen), and TTF-1 (Thyroid transcription factor-1) negativity confirmed metastatic ovarian MCC. There was no evidence of recurrence or metastasis at 12 months after salpingo-oopherectomy.
Conclusion: MCC should be considered in the differential diagnosis of primary and metastatic undifferentiated small round cell tumors of the ovary. |
| first_indexed | 2024-04-10T14:24:27Z |
| format | Article |
| id | doaj.art-d47979f9e2b0432a87ee793d79cd2d3e |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T14:24:27Z |
| publishDate | 2014-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-d47979f9e2b0432a87ee793d79cd2d3e2023-02-15T16:09:11ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312014-12-0131435635910.5152/balkanmedj.2014.14117A Unique Case of Merkel Cell Carcinoma with Ovarian MetastasisArbil Açıkalın0Aysun Uğuz1Derya Gümürdülü2Semra Paydaş3Ümran Küçükgöz Güleç4Department of Pathology, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Pathology, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Pathology, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Medical Oncology, Çukurova University Faculty of Medicine, Adana, TurkeyDepartment of Gynecology and Obstetrics, Çukurova University Faculty of Medicine, Adana, TurkeyBackground: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal malignancy with very aggressive biology and increasing incidence. Ovarian metastasis is an exceptionally rare site for MCC, and only two cases have been reported in the literature. Case Report: We report MCC with ovarian metastasis. A 34 year-old female with previously excised MCC from preauricular skin presented with a pelvic mass 15 months after first diagnosis. Anti-cytokeratin (CK) 20 positivity, LCA (leucocyte common antigen), and TTF-1 (Thyroid transcription factor-1) negativity confirmed metastatic ovarian MCC. There was no evidence of recurrence or metastasis at 12 months after salpingo-oopherectomy. Conclusion: MCC should be considered in the differential diagnosis of primary and metastatic undifferentiated small round cell tumors of the ovary.http://balkanmedicaljournal.org/text.php?lang=en&id=277CarcinomaMerkel cellmetastasis ovarianneoplasms |
| spellingShingle | Arbil Açıkalın Aysun Uğuz Derya Gümürdülü Semra Paydaş Ümran Küçükgöz Güleç A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis Balkan Medical Journal Carcinoma Merkel cell metastasis ovarian neoplasms |
| title | A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis |
| title_full | A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis |
| title_fullStr | A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis |
| title_full_unstemmed | A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis |
| title_short | A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis |
| title_sort | unique case of merkel cell carcinoma with ovarian metastasis |
| topic | Carcinoma Merkel cell metastasis ovarian neoplasms |
| url | http://balkanmedicaljournal.org/text.php?lang=en&id=277 |
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