BDE-47 Induces Mitochondrial Dysfunction and Endoplasmic Reticulum Stress to Inhibit Early Porcine Embryonic Development

BDE-47 Induces Mitochondrial Dysfunction and Endoplasmic Reticulum Stress to Inhibit Early Porcine Embryonic Development

Widely used as a flame retardant, 2,2′4,4′-tetrabromodiphenyl ether (BDE-47) is a persistent environmental pollutant with toxicological effects, including hepatotoxicity, neurotoxicity, reproductive toxicity, and endocrine disruption. To investigate the toxicological effects of BDE-47 on early porci...

Full description

Bibliographic Details
Main Authors:	Rong-Ping Liu, Sheng-Yan He, Jing Wang, Xin-Qin Wang, Zhe-Long Jin, Hao Guo, Chao-Rui Wang, Yong-Nan Xu, Nam-Hyung Kim
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Animals
Subjects:	BDE-47 embryonic development antioxidant endoplasmic reticulum mitochondrial
Online Access:	https://www.mdpi.com/2076-2615/13/14/2291

Similar Items

BDE-47 induces nephrotoxicity through ROS-dependent pathways of mitochondrial dynamics in PK15 cells
by: Shiyao Sun, et al.
Published: (2021-10-01)

Gestational exposure to BDE-209 induces placental injury via the endoplasmic reticulum stress-mediated PERK/ATF4/CHOP signaling pathway
by: Yan Zhao, et al.
Published: (2022-03-01)

Establishment of a comprehensive method to derive seawater quality criteria of BDE-47 in China
by: Dan-Dan Tan, et al.
Published: (2022-08-01)

Interaction of BDE-47 with nuclear receptors (NRs) based on the cytotoxicity: In vitro investigation and molecular interaction
by: Jiayi Song, et al.
Published: (2021-01-01)

Effects of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) on reproductive and endocrine function in female zebrafish (Danio rerio)
by: Xiaoling Shi, et al.
Published: (2022-12-01)

Toxicity Effects of Combined Mixtures of BDE-47 and Nickel on the Microalgae <i>Phaeodactylum tricornutum</i> (Bacillariophyceae)
by: Xiaolai Shi, et al.
Published: (2022-04-01)

Integrated Proteomic and Metabolomic Analysis of the Testes Characterizes BDE-47-Induced Reproductive Toxicity in Mice
by: Liang Xu, et al.
Published: (2021-05-01)

Transcriptomics-based analysis of co-exposure of cadmium (Cd) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) indicates mitochondrial dysfunction induces NLRP3 inflammasome and inflammatory cell death in renal tubular epithelial cells
by: Yi Zhang, et al.
Published: (2022-08-01)

Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus
by: Kui Ding, et al.
Published: (2023-11-01)

RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress
by: Xiao Chen, et al.
Published: (2022-08-01)

Purine Metabolism and Pyrimidine Metabolism Alteration Is a Potential Mechanism of BDE-47-Induced Apoptosis in Marine Rotifer <i>Brachionus plicatilis</i>
by: Sai Cao, et al.
Published: (2023-08-01)

Zearalenone induces mitochondria-associated endoplasmic reticulum membranes dysfunction in piglet Sertoli cells based on endoplasmic reticulum stress
by: Li Ma, et al.
Published: (2023-04-01)

Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis
by: Cheng-Qiang Wang, et al.
Published: (2023-07-01)

The endoplasmic reticulum of trypanosomatids: An unrevealed road for chemotherapy
by: Jana Messias Sandes, et al.
Published: (2022-11-01)

Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes
by: I. Golic, et al.
Published: (2014-09-01)

Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress
by: Jinzhong Jing, et al.
Published: (2023-06-01)

Exploring the role of Prx II in mitigating endoplasmic reticulum stress and mitochondrial dysfunction in neurodegeneration
by: Mei-Hua Jin, et al.
Published: (2024-04-01)

On the Role of Aminochrome in Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Parkinson's Disease
by: Juan Segura-Aguilar
Published: (2019-03-01)

Retracted: Wogonoside promotes apoptosis in gastric cancer AGS and SGC‐7901 cells through induction of mitochondrial dysfunction and endoplasmic reticulum stress
by: Xiao‐Miao Hu, et al.
Published: (2019-08-01)

Mitochondrial pathway and endoplasmic reticulum stress participate in the photosensitizing effectiveness of AE‐PDT in MG63 cells
by: Kai‐Ting Li, et al.
Published: (2016-11-01)

Endoplasmic reticulum quality control and dysmyelination
by: Kraus Allison, et al.
Published: (2011-08-01)

Inhibition of Mitochondrial Fission Alleviates Zearalenone-Induced Mitochondria-Associated Endoplasmic Reticulum Membrane Dysfunction in Piglet Sertoli Cells
by: Li Ma, et al.
Published: (2023-03-01)

Mitochondrial dysfunction and endoplasmic reticulum stress induced by activation of PPARα leaded testicular to apoptosis in SD rats explored to di-(2-ethylhexyl) phthalate (DEHP)
by: Haoyang Zhang, et al.
Published: (2023-12-01)

Toxic effects of decabromodiphenyl ether (BDE-209) on human embryonic kidney cells
by: Min eLi, et al.
Published: (2014-05-01)

Behavioral changes and transcriptomic effects at embryonic and post-embryonic stages reveal the toxic effects of 2,2′,4,4′-tetrabromodiphenyl ether on neurodevelopment in zebrafish (Danio rerio)
by: Shukai Zheng, et al.
Published: (2022-12-01)

Effects of homocysteine-induced endoplasmic reticulum protein on endoplasmic reticulum stress, autophagy, and neuronal apoptosis following intracerebral hemorrhage
by: Hui Wu, et al.
Published: (2020-12-01)

The Molecular Mechanisms Underlying Mitochondria-Associated Endoplasmic Reticulum Membrane-Induced Insulin Resistance
by: Han Cheng, et al.
Published: (2020-11-01)

Chemotherapy Resistance Explained through Endoplasmic Reticulum Stress-Dependent Signaling
by: Entaz Bahar, et al.
Published: (2019-03-01)

Autophagy Mediates <i>Escherichia Coli</i>-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress
by: Jianguo Liu, et al.
Published: (2022-11-01)

The Interplay of Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress in Cardiovascular Fibrosis in Obese Rats
by: Francisco V. Souza-Neto, et al.
Published: (2021-08-01)

Neuroprotective Effects of the Neural-Induced Adipose-Derived Stem Cell Secretome against Rotenone-Induced Mitochondrial and Endoplasmic Reticulum Dysfunction
by: Mahesh Ramalingam, et al.
Published: (2023-03-01)

Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis
by: Lingna Xu, et al.
Published: (2020-07-01)

Angiotensin-converting enzyme 2 regulates endoplasmic reticulum stress and mitochondrial function to preserve skeletal muscle lipid metabolism
by: Xi Cao, et al.
Published: (2019-11-01)

Glycoprotein Quality Control and Endoplasmic Reticulum Stress
by: Qian Wang, et al.
Published: (2015-07-01)

Chitosan nanoparticles induced the antitumor effect in hepatocellular carcinoma cells by regulating ROS-mediated mitochondrial damage and endoplasmic reticulum stress
by: Yibing Jiang, et al.
Published: (2019-12-01)

Transcriptomic Analysis of Gonadal Adipose Tissue in Male Mice Exposed Perinatally to 2,2′,4,4′-Tetrabromodiphenyl Ether (BDE-47)
by: Aser Abrha, et al.
Published: (2018-03-01)

Effects of decabromodiphenyl ether (BDE-209) on a mangrove plant, Kandelia obovata and the uptake, translocation and accumulation of BDE-209
by: Ying Wang, et al.
Published: (2022-07-01)

Endoplasmic Reticulum (ER) Stress and Apoptosis in Parthenogenetic Porcine Embryos following Different Combination of Activation Methods
by: Hye-Bin Park, et al.
Published: (2017-03-01)

Research advances of endoplasmic reticulum stress in high glucose environment and its related ophthalmic diseases
by: Jia-Jun Lu, et al.
Published: (2018-06-01)

Morphological Heterogeneity of the Endoplasmic Reticulum within Neurons and Its Implications in Neurodegeneration
by: Sreesha Sree, et al.
Published: (2021-04-01)