RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation.

RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation.

RAGE, receptor for advanced glycation endoproducts (AGE), has been characterized as an activator of osteoclastgenesis. However, whether RAGE directly regulates chondrocyte proliferation and differentiation is unclear. Here, we show that RAGE has an inhibitory role in chondrocyte differentiation. RAG...

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Bibliographic Details
Main Authors: Tatsuya Kosaka, Rino Fukui, Mio Matsui, Yuko Kurosaka, Haruka Nishimura, Motoki Tanabe, Yuuki Takakura, Keisuke Iwai, Takuya Waki, Takashi Fujita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4183532?pdf=render

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