Techniques for Molecular Imaging Probe Design
Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2011-11-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.2310/7290.2011.00003 |
| _version_ | 1826904111909437440 |
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| author | Fred Reynolds Kimberly A. Kelly |
| author_facet | Fred Reynolds Kimberly A. Kelly |
| author_sort | Fred Reynolds |
| collection | DOAJ |
| description | Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents. |
| first_indexed | 2024-03-07T17:04:16Z |
| format | Article |
| id | doaj.art-d48044eaa98a44f3b0180e4f4e119824 |
| institution | Directory Open Access Journal |
| issn | 1536-0121 |
| language | English |
| last_indexed | 2025-02-17T08:06:05Z |
| publishDate | 2011-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Molecular Imaging |
| spelling | doaj.art-d48044eaa98a44f3b0180e4f4e1198242025-01-03T00:11:22ZengSAGE PublishingMolecular Imaging1536-01212011-11-011010.2310/7290.2011.0000310.2310_7290.2011.00003Techniques for Molecular Imaging Probe DesignFred ReynoldsKimberly A. KellyMolecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.https://doi.org/10.2310/7290.2011.00003 |
| spellingShingle | Fred Reynolds Kimberly A. Kelly Techniques for Molecular Imaging Probe Design Molecular Imaging |
| title | Techniques for Molecular Imaging Probe Design |
| title_full | Techniques for Molecular Imaging Probe Design |
| title_fullStr | Techniques for Molecular Imaging Probe Design |
| title_full_unstemmed | Techniques for Molecular Imaging Probe Design |
| title_short | Techniques for Molecular Imaging Probe Design |
| title_sort | techniques for molecular imaging probe design |
| url | https://doi.org/10.2310/7290.2011.00003 |
| work_keys_str_mv | AT fredreynolds techniquesformolecularimagingprobedesign AT kimberlyakelly techniquesformolecularimagingprobedesign |