Orofacial Crohn’s Disease: A Case Report
Crohn’s disease (CD) is a chronic disease of the digestive system. It is characterized by lesions predominantly located in the small intestine and colon, although they may also occur in any segment of the gut, including the oral cavity. The involvement of oral mucosa in CD may be underreported, as u...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2019-12-01
|
| Series: | Journal of Pediatric Research |
| Subjects: | |
| Online Access: |
http://jpedres.org/archives/archive-detail/article-preview/orofacial-crohns-disease-a-case-report/25489
|
| _version_ | 1797909587453542400 |
|---|---|
| author | Miray Karakoyun Ezgi Kiran Taşcı Murat Sezak Burçe Emine Yaşar Funda Çetin |
| author_facet | Miray Karakoyun Ezgi Kiran Taşcı Murat Sezak Burçe Emine Yaşar Funda Çetin |
| author_sort | Miray Karakoyun |
| collection | DOAJ |
| description | Crohn’s disease (CD) is a chronic disease of the digestive system. It is characterized by lesions predominantly located in the small intestine and colon, although they may also occur in any segment of the gut, including the oral cavity. The involvement of oral mucosa in CD may be underreported, as up to 42% of pediatric patients with CD were found to have oral lesions after undergoing a thorough oral examination. Here, we present a case of CD in which the patient was referred to a dentist due to non-healing aphthous ulcers in the mouth. Our patient, a 16-year-old boy, was admitted to the dentistry clinic with swelling of the oral mucosa and the lips which had been ongoing for 3 months. The patient was referred to our department due to the non-response of the mucosal lesions to repeated cycles of medical treatment. Colonoscopy revealed a cobblestone appearance especially in the left colon, partly normal mucosa, and exudative ulcers. Biopsy samples showed increased inflammatory cell infiltration in the lamina propria and cryptitis in some of the crypts. A close collaboration between gastroenterologists and dentists is useful when addressing the diagnosis and appropriate management of these patients. |
| first_indexed | 2024-04-10T11:10:39Z |
| format | Article |
| id | doaj.art-d48052f8d52a4d2da15ec07057ddc063 |
| institution | Directory Open Access Journal |
| issn | 2147-9445 2587-2478 |
| language | English |
| last_indexed | 2024-04-10T11:10:39Z |
| publishDate | 2019-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Pediatric Research |
| spelling | doaj.art-d48052f8d52a4d2da15ec07057ddc0632023-02-15T16:19:09ZengGalenos YayineviJournal of Pediatric Research2147-94452587-24782019-12-016435335510.4274/jpr.galenos.2019.2621313049054Orofacial Crohn’s Disease: A Case ReportMiray Karakoyun0Ezgi Kiran Taşcı1Murat Sezak2Burçe Emine Yaşar3Funda Çetin4 Ege University Faculty of Medicine, Department of Pediatric Gastroenterology, Division of Hepatology and Nutrition, İzmir, Turkey Ege University Faculty of Medicine, Department of Pediatric Gastroenterology, Division of Hepatology and Nutrition, İzmir, Turkey Ege University Faculty of Medicine, Department of Pathology, İzmir, Turkey Ege University Faculty of Medicine, Department of Pediatrics, İzmir, Turkey Ege University Faculty of Medicine, Department of Pediatric Gastroenterology, Division of Hepatology and Nutrition, İzmir, Turkey Crohn’s disease (CD) is a chronic disease of the digestive system. It is characterized by lesions predominantly located in the small intestine and colon, although they may also occur in any segment of the gut, including the oral cavity. The involvement of oral mucosa in CD may be underreported, as up to 42% of pediatric patients with CD were found to have oral lesions after undergoing a thorough oral examination. Here, we present a case of CD in which the patient was referred to a dentist due to non-healing aphthous ulcers in the mouth. Our patient, a 16-year-old boy, was admitted to the dentistry clinic with swelling of the oral mucosa and the lips which had been ongoing for 3 months. The patient was referred to our department due to the non-response of the mucosal lesions to repeated cycles of medical treatment. Colonoscopy revealed a cobblestone appearance especially in the left colon, partly normal mucosa, and exudative ulcers. Biopsy samples showed increased inflammatory cell infiltration in the lamina propria and cryptitis in some of the crypts. A close collaboration between gastroenterologists and dentists is useful when addressing the diagnosis and appropriate management of these patients. http://jpedres.org/archives/archive-detail/article-preview/orofacial-crohns-disease-a-case-report/25489 crohn’s diseaseoral cavitydentist |
| spellingShingle | Miray Karakoyun Ezgi Kiran Taşcı Murat Sezak Burçe Emine Yaşar Funda Çetin Orofacial Crohn’s Disease: A Case Report Journal of Pediatric Research crohn’s disease oral cavity dentist |
| title | Orofacial Crohn’s Disease: A Case Report |
| title_full | Orofacial Crohn’s Disease: A Case Report |
| title_fullStr | Orofacial Crohn’s Disease: A Case Report |
| title_full_unstemmed | Orofacial Crohn’s Disease: A Case Report |
| title_short | Orofacial Crohn’s Disease: A Case Report |
| title_sort | orofacial crohn s disease a case report |
| topic | crohn’s disease oral cavity dentist |
| url |
http://jpedres.org/archives/archive-detail/article-preview/orofacial-crohns-disease-a-case-report/25489
|
| work_keys_str_mv | AT miraykarakoyun orofacialcrohnsdiseaseacasereport AT ezgikirantascı orofacialcrohnsdiseaseacasereport AT muratsezak orofacialcrohnsdiseaseacasereport AT burceemineyasar orofacialcrohnsdiseaseacasereport AT fundacetin orofacialcrohnsdiseaseacasereport |