Transcriptomic Analysis in Multiple Myeloma and Primary Plasma Cell Leukemia with t(11;14) Reveals Different Expression Patterns with Biological Implications in Venetoclax Sensitivity

Transcriptomic Analysis in Multiple Myeloma and Primary Plasma Cell Leukemia with t(11;14) Reveals Different Expression Patterns with Biological Implications in Venetoclax Sensitivity

Mechanisms underlying the pathophysiology of primary Plasma Cell Leukemia (pPCL) and intramedullary multiple myeloma (MM) need to be further elucidated, being potentially relevant for improving therapeutic approaches. In such a context, the MM and pPCL subgroups characterized by t(11;14) deserve a f...

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Bibliographic Details
Main Authors: Katia Todoerti, Elisa Taiana, Noemi Puccio, Vanessa Favasuli, Marta Lionetti, Ilaria Silvestris, Massimo Gentile, Pellegrino Musto, Fortunato Morabito, Umberto Gianelli, Niccolò Bolli, Luca Baldini, Antonino Neri, Domenica Ronchetti
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
t(11
14)
multiple myeloma
Plasma Cell Leukemia
venetoclax
lncRNA
Online Access:https://www.mdpi.com/2072-6694/13/19/4898

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