The Study on Timolol and Its Potential Phototoxicity Using Chemical, In Silico and In Vitro Methods

The Study on Timolol and Its Potential Phototoxicity Using Chemical, In Silico and In Vitro Methods

Timolol (TIM) is a non-selective ß-adrenergic receptor antagonist used orally for the treatment of hypertension and heart attacks, and topically for treating glaucoma; lately, it has also been used in some specific dermatological problems. In the present study, its photodegradation and potential ris...

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Bibliographic Details
Main Authors: Karolina Lejwoda, Anna Gumieniczek, Agata Filip, Beata Naumczuk
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceuticals
Subjects:
timolol
photodegradation
phototoxicity
LC-UV and UPLC-HRMS
ROS generation
in vitro tests
Online Access:https://www.mdpi.com/1424-8247/17/1/98

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