Implication of endoplasmic reticulum stress and mitochondrial perturbations in remote liver injury after renal ischemia/reperfusion in rats: potential protective role of azilsartan

Implication of endoplasmic reticulum stress and mitochondrial perturbations in remote liver injury after renal ischemia/reperfusion in rats: potential protective role of azilsartan

ABSTRACTObjectives: Distant liver injury is a complication of renal ischemia-reperfusion (I/R) injury, which imposes mortality and economic burden. This study aimed to elucidate the cross-talk of endoplasmic reticulum (ER) stress and mitochondrial perturbations in renal I/R-induced liver injury, and...

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Bibliographic Details
Main Authors:	Rania A. Elrashidy, Esraa M. Zakaria, Rehab A. Hasan, Asmaa M. Elmaghraby, Dina A. Hassan, Ranya M. Abdelgalil, Shaimaa R. Abdelmohsen, Amira M. Negm, Azza S. Khalil, Ayat M. S. Eraque, Reem M. Ahmed, Walaa S. Sabbah, Ahmed A. Ahmed, Samah E. Ibrahim
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Redox Report
Subjects:	Azilsartan Renal ischemia/reperfusion Remote liver injury Endoplasmic reticulum stress CHOP Mitochondrial biogenesis
Online Access:	https://www.tandfonline.com/doi/10.1080/13510002.2024.2319963

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