Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men
Background and Objectives: Irisin hormone is released from muscle cells by exercise and exerts its positive effects through increasing energy expenditure, and considering the anti-inflammatory effect of Interleukin (IL)-10 in response to systemic inflammation, this research eas performed with the pu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | fas |
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Qom University of Medical Sciences
2018-04-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| Subjects: | |
| Online Access: | http://journal.muq.ac.ir/browse.php?a_code=A-10-851-1&slc_lang=en&sid=1 |
| _version_ | 1818722688628162560 |
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| author | hasan vahdat Hojatallah Mombini Mohsen Eslami Farsani Shima Ab Abzadeh Hossein Barzegar |
| author_facet | hasan vahdat Hojatallah Mombini Mohsen Eslami Farsani Shima Ab Abzadeh Hossein Barzegar |
| author_sort | hasan vahdat |
| collection | DOAJ |
| description | Background and Objectives: Irisin hormone is released from muscle cells by exercise and exerts its positive effects through increasing energy expenditure, and considering the anti-inflammatory effect of Interleukin (IL)-10 in response to systemic inflammation, this research eas performed with the purpose of determining the effect of one period of High-Intensity Interval Training (HIIT) on serum levels of irisin and IL-10 in overweight men.
Methods: In this experimental study, 20 men in the age range of (35-45 year) with body mass index of (25-30kg/m2), were selected and randomly divided into two equal groups of control and exercises. The exercise group carried out HIIT training for 6 weeks. At baseline and the end of the study, blood sampling and serum preparation were performed and the levels of irisin hormone and IL-10, were measured by ELISA method. The data were analyzed by Kolmogorov - Smirnov and t-tests at the significance level of p<0.05.
Results: IL-10 serum level showed a significant increase in the of post-test in the exercise group (p<0.001). While, there was no difference between the two groups in the pre-test. Despite a little increase in the irisin level in the post-test of exercise group, the difference was not statistically significant. Also, intra-group comparison of pre-test and post-test of eacg group, only in the post-test IL-10 of the training group, the results were significant (p>0.05).
Conclusion: It seems that 6 weeks of HIIT training has a positive effect on anti-inflammatory factors, especially IL-10 level in overweight men, while, it has less effect on the level of irisin hormone in these subjects.
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| first_indexed | 2024-12-17T20:58:36Z |
| format | Article |
| id | doaj.art-d4912e24908f45488fa0127f2f3a176b |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-17T20:58:36Z |
| publishDate | 2018-04-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-d4912e24908f45488fa0127f2f3a176b2022-12-21T21:32:48ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752018-04-011223544Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Menhasan vahdat0Hojatallah Mombini1Mohsen Eslami Farsani2Shima Ab Abzadeh3Hossein Barzegar4 Department of Physical Education & Sport Sciences, Faculty of Physical Education, University of Tehran, Tehran, Iran. Department of Physical Education & Sport Sciences, Faculty of Physical Education, University of Tehran, Tehran, Iran. Department of Anatomy, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran. Department of Anatomy, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran. Department of Physical Education & Sport Sciences, Faculty of Physical Education, University of Tehran, Tehran, Iran. Background and Objectives: Irisin hormone is released from muscle cells by exercise and exerts its positive effects through increasing energy expenditure, and considering the anti-inflammatory effect of Interleukin (IL)-10 in response to systemic inflammation, this research eas performed with the purpose of determining the effect of one period of High-Intensity Interval Training (HIIT) on serum levels of irisin and IL-10 in overweight men. Methods: In this experimental study, 20 men in the age range of (35-45 year) with body mass index of (25-30kg/m2), were selected and randomly divided into two equal groups of control and exercises. The exercise group carried out HIIT training for 6 weeks. At baseline and the end of the study, blood sampling and serum preparation were performed and the levels of irisin hormone and IL-10, were measured by ELISA method. The data were analyzed by Kolmogorov - Smirnov and t-tests at the significance level of p<0.05. Results: IL-10 serum level showed a significant increase in the of post-test in the exercise group (p<0.001). While, there was no difference between the two groups in the pre-test. Despite a little increase in the irisin level in the post-test of exercise group, the difference was not statistically significant. Also, intra-group comparison of pre-test and post-test of eacg group, only in the post-test IL-10 of the training group, the results were significant (p>0.05). Conclusion: It seems that 6 weeks of HIIT training has a positive effect on anti-inflammatory factors, especially IL-10 level in overweight men, while, it has less effect on the level of irisin hormone in these subjects. http://journal.muq.ac.ir/browse.php?a_code=A-10-851-1&slc_lang=en&sid=1irisin interleukins high-intensity interval training interleukin-10. irisin interleukins high-intensity interval training interleukin-10. |
| spellingShingle | hasan vahdat Hojatallah Mombini Mohsen Eslami Farsani Shima Ab Abzadeh Hossein Barzegar Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum irisin interleukins high-intensity interval training interleukin-10. irisin interleukins high-intensity interval training interleukin-10. |
| title | Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men |
| title_full | Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men |
| title_fullStr | Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men |
| title_full_unstemmed | Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men |
| title_short | Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men |
| title_sort | effect of high intensity interval training hiit on the levels of irisin and interleukin 10 in overweight men |
| topic | irisin interleukins high-intensity interval training interleukin-10. irisin interleukins high-intensity interval training interleukin-10. |
| url | http://journal.muq.ac.ir/browse.php?a_code=A-10-851-1&slc_lang=en&sid=1 |
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