Cochlear implantation in patients with Meniere's disease: A systematic review
Background: Meniere's disease (MD) is an idiopathic disorder of the inner ear, which manifests as cochleo-vestibular dysfunction. Hearing loss will progress to a profound levelin a subset of patients with MD, and vestibular interventions can independently cause loss of hearing. The aim of this...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-10-01
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| Series: | World Journal of Otorhinolaryngology-Head and Neck Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095881120300329 |
| _version_ | 1811319677514678272 |
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| author | Vincent M. Desiato Jaimin J. Patel Shaun A. Nguyen Ted A. Meyer Paul R. Lambert |
| author_facet | Vincent M. Desiato Jaimin J. Patel Shaun A. Nguyen Ted A. Meyer Paul R. Lambert |
| author_sort | Vincent M. Desiato |
| collection | DOAJ |
| description | Background: Meniere's disease (MD) is an idiopathic disorder of the inner ear, which manifests as cochleo-vestibular dysfunction. Hearing loss will progress to a profound levelin a subset of patients with MD, and vestibular interventions can independently cause loss of hearing. The aim of this study was to systematically review the published literature describing the safety and efficacy of CI in patients with MD. Materials and methods: A systematic literature review was conducted in accordance PRISMA guidelines to identify articles that assessed at least one functional outcome in patients with MD who underwent CI. Demographic information, disease history, MD symptoms, outcomes measures, and complications related to CI were extracted from included studies. Results: In total, 17 studies were included, and 182 patients with MD underwent CI. The weighted-mean age was 61.9 years (range 27–85). Study objective and methodology varied, and there was significant heterogeneity in CI outcome measures reported. In total, 179 (98.3%) of 182 patients reported objective improvements in at least one hearing metric after CI. A total of 69 patients (37.9%) reported vertigo or severe dizziness prior to CI, compared to 22 patients (15.4%) postoperatively. Two studies reported significant reductions in postoperative Tinnitus Handicap Inventory score (THI). Quality of life assessments varied between studies. Complications rates were low with only nine patients (4.9%) reporting a serious CI-related complication. Conclusions: This systematic review evaluated 17 studies describing the safety and efficacy of CI in patients with MD and encountered many challenges due to small sample sizes, and heterogeneity in study design and outcomes measured. Despite these limitations, this study of 182 patients is to the best of our knowledge the largest systematic review evaluating the safety and efficacy of CI in MD. The results of this study support the need for a standardized approach to evaluating outcomes of CI in patients with MD in future studies. |
| first_indexed | 2024-04-13T12:46:53Z |
| format | Article |
| id | doaj.art-d49946b1e33f41d3b87f020a97aeb39f |
| institution | Directory Open Access Journal |
| issn | 2095-8811 |
| language | English |
| last_indexed | 2024-04-13T12:46:53Z |
| publishDate | 2021-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | World Journal of Otorhinolaryngology-Head and Neck Surgery |
| spelling | doaj.art-d49946b1e33f41d3b87f020a97aeb39f2022-12-22T02:46:21ZengWileyWorld Journal of Otorhinolaryngology-Head and Neck Surgery2095-88112021-10-0174303311Cochlear implantation in patients with Meniere's disease: A systematic reviewVincent M. Desiato0Jaimin J. Patel1Shaun A. Nguyen2Ted A. Meyer3Paul R. Lambert4Corresponding author. Medical University of South Carolina, 135 Rutledge Ave, MSC 550, Charleston, SC, 29425-5500, USA.; Department of Otolaryngology- Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USADepartment of Otolaryngology- Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USADepartment of Otolaryngology- Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USADepartment of Otolaryngology- Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USADepartment of Otolaryngology- Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USABackground: Meniere's disease (MD) is an idiopathic disorder of the inner ear, which manifests as cochleo-vestibular dysfunction. Hearing loss will progress to a profound levelin a subset of patients with MD, and vestibular interventions can independently cause loss of hearing. The aim of this study was to systematically review the published literature describing the safety and efficacy of CI in patients with MD. Materials and methods: A systematic literature review was conducted in accordance PRISMA guidelines to identify articles that assessed at least one functional outcome in patients with MD who underwent CI. Demographic information, disease history, MD symptoms, outcomes measures, and complications related to CI were extracted from included studies. Results: In total, 17 studies were included, and 182 patients with MD underwent CI. The weighted-mean age was 61.9 years (range 27–85). Study objective and methodology varied, and there was significant heterogeneity in CI outcome measures reported. In total, 179 (98.3%) of 182 patients reported objective improvements in at least one hearing metric after CI. A total of 69 patients (37.9%) reported vertigo or severe dizziness prior to CI, compared to 22 patients (15.4%) postoperatively. Two studies reported significant reductions in postoperative Tinnitus Handicap Inventory score (THI). Quality of life assessments varied between studies. Complications rates were low with only nine patients (4.9%) reporting a serious CI-related complication. Conclusions: This systematic review evaluated 17 studies describing the safety and efficacy of CI in patients with MD and encountered many challenges due to small sample sizes, and heterogeneity in study design and outcomes measured. Despite these limitations, this study of 182 patients is to the best of our knowledge the largest systematic review evaluating the safety and efficacy of CI in MD. The results of this study support the need for a standardized approach to evaluating outcomes of CI in patients with MD in future studies.http://www.sciencedirect.com/science/article/pii/S2095881120300329Cochlear implantationMeniere's disease |
| spellingShingle | Vincent M. Desiato Jaimin J. Patel Shaun A. Nguyen Ted A. Meyer Paul R. Lambert Cochlear implantation in patients with Meniere's disease: A systematic review World Journal of Otorhinolaryngology-Head and Neck Surgery Cochlear implantation Meniere's disease |
| title | Cochlear implantation in patients with Meniere's disease: A systematic review |
| title_full | Cochlear implantation in patients with Meniere's disease: A systematic review |
| title_fullStr | Cochlear implantation in patients with Meniere's disease: A systematic review |
| title_full_unstemmed | Cochlear implantation in patients with Meniere's disease: A systematic review |
| title_short | Cochlear implantation in patients with Meniere's disease: A systematic review |
| title_sort | cochlear implantation in patients with meniere s disease a systematic review |
| topic | Cochlear implantation Meniere's disease |
| url | http://www.sciencedirect.com/science/article/pii/S2095881120300329 |
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