Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization

The tissue inclusion parameter estimation method is proposed to measure the stiffness as well as geometric parameters. The estimation is performed based on the tactile data obtained at the surface of the tissue using an optical tactile sensation imaging system (TSIS). A forward algorithm is desi...

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Main Authors: Jong-Ha Lee, Yoon Nyun Kim, Hee-Jun Park
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/15/3/6306
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author Jong-Ha Lee
Yoon Nyun Kim
Hee-Jun Park
author_facet Jong-Ha Lee
Yoon Nyun Kim
Hee-Jun Park
author_sort Jong-Ha Lee
collection DOAJ
description The tissue inclusion parameter estimation method is proposed to measure the stiffness as well as geometric parameters. The estimation is performed based on the tactile data obtained at the surface of the tissue using an optical tactile sensation imaging system (TSIS). A forward algorithm is designed to comprehensively predict the tactile data based on the mechanical properties of tissue inclusion using finite element modeling (FEM). This forward information is used to develop an inversion algorithm that will be used to extract the size, depth, and Young's modulus of a tissue inclusion from the tactile data. We utilize the artificial neural network (ANN) for the inversion algorithm. The proposed estimation method was validated by a realistic tissue phantom with stiff inclusions. The experimental results showed that the proposed estimation method can measure the size, depth, and Young's modulus of a tissue inclusion with 0.58%, 3.82%, and 2.51% relative errors, respectively. The obtained results prove that the proposed method has potential to become a useful screening and diagnostic method for breast cancer.
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spelling doaj.art-d49a3b38ec1c4e77b3419d881199e2b92022-12-22T03:59:18ZengMDPI AGSensors1424-82202015-03-011536306632310.3390/s150306306s150306306Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue CharacterizationJong-Ha Lee0Yoon Nyun Kim1Hee-Jun Park2Department of Biomedical Engineering, School of Medicine, Keimyung University, 1095, Dalgubeol-daero, Daegu 704-701, KoreaDepartment of Internal Medicine, Dongsan Medical Center, Keimyung University, 1095, Dalgubeol-daero, Daegu 704-701, KoreaDepartment of Biomedical Engineering, School of Medicine, Keimyung University, 1095, Dalgubeol-daero, Daegu 704-701, KoreaThe tissue inclusion parameter estimation method is proposed to measure the stiffness as well as geometric parameters. The estimation is performed based on the tactile data obtained at the surface of the tissue using an optical tactile sensation imaging system (TSIS). A forward algorithm is designed to comprehensively predict the tactile data based on the mechanical properties of tissue inclusion using finite element modeling (FEM). This forward information is used to develop an inversion algorithm that will be used to extract the size, depth, and Young's modulus of a tissue inclusion from the tactile data. We utilize the artificial neural network (ANN) for the inversion algorithm. The proposed estimation method was validated by a realistic tissue phantom with stiff inclusions. The experimental results showed that the proposed estimation method can measure the size, depth, and Young's modulus of a tissue inclusion with 0.58%, 3.82%, and 2.51% relative errors, respectively. The obtained results prove that the proposed method has potential to become a useful screening and diagnostic method for breast cancer.http://www.mdpi.com/1424-8220/15/3/6306tumor detectionartificial palpationlesion characterizationtactile sensorbiomimetic sensorYoung’s modulus
spellingShingle Jong-Ha Lee
Yoon Nyun Kim
Hee-Jun Park
Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
Sensors
tumor detection
artificial palpation
lesion characterization
tactile sensor
biomimetic sensor
Young’s modulus
title Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
title_full Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
title_fullStr Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
title_full_unstemmed Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
title_short Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization
title_sort bio optics based sensation imaging for breast tumor detection using tissue characterization
topic tumor detection
artificial palpation
lesion characterization
tactile sensor
biomimetic sensor
Young’s modulus
url http://www.mdpi.com/1424-8220/15/3/6306
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AT yoonnyunkim bioopticsbasedsensationimagingforbreasttumordetectionusingtissuecharacterization
AT heejunpark bioopticsbasedsensationimagingforbreasttumordetectionusingtissuecharacterization