Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?

Aim of the work: The aim of this study was to assess the rule of delayed T1 post contrast sequence in detection of active lesions in multiple sclerosis patients by comparing the early and delayed T1 post contrast images. Materials: This was a prospective study and included 30 known multiple sclerosi...

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Main Authors: Doaa M. Emara, Amr M. El Abd, Amr M. El Fatatry
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S0378603X17302206
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author Doaa M. Emara
Amr M. El Abd
Amr M. El Fatatry
author_facet Doaa M. Emara
Amr M. El Abd
Amr M. El Fatatry
author_sort Doaa M. Emara
collection DOAJ
description Aim of the work: The aim of this study was to assess the rule of delayed T1 post contrast sequence in detection of active lesions in multiple sclerosis patients by comparing the early and delayed T1 post contrast images. Materials: This was a prospective study and included 30 known multiple sclerosis patients with clinically suspected activity referred form neurology department to radiology department for MRI examination. Methods: All patients were subjected to the followings:– Conventional routine MRI of the brain using 1.5 T machine.– T1 delayed post contrast sequence (about 10 min after contrast injection). Results: The included MS cases showed 162 lesions of variable distribution as 113 lesions were supratentorial while 49 lesions were infratentorial. Among 162 lesions in the current cases 58 lesions showed post contrast enhancement while the remaining 104 lesions were non enhancing. From the total of enhancing lesions (58), 16 lesions showed early enhancement while 42 lesions showed delayed enhancement. Conclusion: Delayed T1 post contrast is an important sequence for detection of active MS plaques as it increases the sensitivity of MRI. Keywords: Delayed T1 post contrast, Multiple sclerosis (MS), Delayed enhancement, MS activity
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spelling doaj.art-d49d768cada3416680300eb553225d672022-12-21T18:23:54ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2018-03-01491181189Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?Doaa M. Emara0Amr M. El Abd1Amr M. El Fatatry2Department of Radiodiagnosis, Faculty of Medicine, Alexandria University, Egypt; Corresponding author at: Department of Diagnostic and Interventional Radiology, Champollion Street, El Azareeta, Faculty of Medicine, Alexandria University Hospital, Egypt.Department of Radiodiagnosis, Faculty of Medicine, Alexandria University, EgyptDepartment of Neuropsychiatry, Faculty of Medicine, Alexandria University, EgyptAim of the work: The aim of this study was to assess the rule of delayed T1 post contrast sequence in detection of active lesions in multiple sclerosis patients by comparing the early and delayed T1 post contrast images. Materials: This was a prospective study and included 30 known multiple sclerosis patients with clinically suspected activity referred form neurology department to radiology department for MRI examination. Methods: All patients were subjected to the followings:– Conventional routine MRI of the brain using 1.5 T machine.– T1 delayed post contrast sequence (about 10 min after contrast injection). Results: The included MS cases showed 162 lesions of variable distribution as 113 lesions were supratentorial while 49 lesions were infratentorial. Among 162 lesions in the current cases 58 lesions showed post contrast enhancement while the remaining 104 lesions were non enhancing. From the total of enhancing lesions (58), 16 lesions showed early enhancement while 42 lesions showed delayed enhancement. Conclusion: Delayed T1 post contrast is an important sequence for detection of active MS plaques as it increases the sensitivity of MRI. Keywords: Delayed T1 post contrast, Multiple sclerosis (MS), Delayed enhancement, MS activityhttp://www.sciencedirect.com/science/article/pii/S0378603X17302206
spellingShingle Doaa M. Emara
Amr M. El Abd
Amr M. El Fatatry
Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
The Egyptian Journal of Radiology and Nuclear Medicine
title Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
title_full Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
title_fullStr Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
title_full_unstemmed Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
title_short Delayed post contrast magnetic resonance imaging (MRI) of the brain in multiple sclerosis (MS) patients: Is it of value?
title_sort delayed post contrast magnetic resonance imaging mri of the brain in multiple sclerosis ms patients is it of value
url http://www.sciencedirect.com/science/article/pii/S0378603X17302206
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