Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice
Introduction Angiotensin II (Ang II) is known to induce cardiac growth and modulate myocardial contractility. It has been reported that elevated levels of endogenous Ang II contribute to the development of cardiac hypertrophy in hypertensives. However, the long-term functional effects of cardiac exp...
Main Authors: | Catherine E Huggins, Andrea A Domenighetti, Thierry Pedrazzini, Salvatore Pepe, Lea MD Delbridge |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2003-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2003.030 |
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