Neoadjuvant immunotherapy for colorectal cancer: Right regimens, right patients, right directions?

Neoadjuvant immunotherapy for colorectal cancer: Right regimens, right patients, right directions?

Neoadjuvant chemoradiotherapy (NACRT) or chemotherapy (NACT) followed by radical resection and then adjuvant therapy is considered the optimal treatment model for locally advanced colorectal cancer (LACRC). A recent total neoadjuvant therapy (TNT) strategy further improved the tumour regression rate...

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Bibliographic Details
Main Authors: Jiahao Zhu, Jie Lian, Benjie Xu, Xiangyi Pang, Shengjun Ji, Yutian Zhao, Haibo Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer
immune checkpoint blockade
immunotherapy
microsatellite instability
neoadjuvant treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1120684/full

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