Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]

Rheumatoid arthritis (RA) is a common autoimmune disease characterized by inflammation of small joints. Small synovial joints in the larynx can also become affected, and laryngeal involvement is seen in more than half of patients with RA. As most patients have subtle symptoms and indolent course, th...

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Main Authors: Mohan Rudrappa, Laxmi Kokatnur, Sanket Shah
Format: Article
Language:English
Published: F1000 Research Ltd 2020-02-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-119/v1
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author Mohan Rudrappa
Laxmi Kokatnur
Sanket Shah
author_facet Mohan Rudrappa
Laxmi Kokatnur
Sanket Shah
author_sort Mohan Rudrappa
collection DOAJ
description Rheumatoid arthritis (RA) is a common autoimmune disease characterized by inflammation of small joints. Small synovial joints in the larynx can also become affected, and laryngeal involvement is seen in more than half of patients with RA. As most patients have subtle symptoms and indolent course, they are either misdiagnosed or undiagnosed. The acute worsening of cricoarytenoid arthritis can cause sudden upper airway obstruction and may require emergency intubation or tracheostomy. This life-threatening condition is described in only a handful of cases in the medical literature. Physicians should be aware of this rare but life-threatening consequence of RA. We present a case of sudden and severe upper airway obstruction secondary to laryngeal involvement in a patient with long-standing RA.
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spelling doaj.art-d4a014e0b5324f95a2663884f8cd1f7c2022-12-21T19:17:32ZengF1000 Research LtdF1000Research2046-14022020-02-01910.12688/f1000research.22256.124550Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]Mohan Rudrappa0Laxmi Kokatnur1Sanket Shah2Department of Medicine, Mercy Hospital, Joplin, MO, USADepartment of Medicine, Mercy Hospital, Joplin, MO, USADepartment of Medicine, Mercy Hospital, Joplin, MO, USARheumatoid arthritis (RA) is a common autoimmune disease characterized by inflammation of small joints. Small synovial joints in the larynx can also become affected, and laryngeal involvement is seen in more than half of patients with RA. As most patients have subtle symptoms and indolent course, they are either misdiagnosed or undiagnosed. The acute worsening of cricoarytenoid arthritis can cause sudden upper airway obstruction and may require emergency intubation or tracheostomy. This life-threatening condition is described in only a handful of cases in the medical literature. Physicians should be aware of this rare but life-threatening consequence of RA. We present a case of sudden and severe upper airway obstruction secondary to laryngeal involvement in a patient with long-standing RA.https://f1000research.com/articles/9-119/v1
spellingShingle Mohan Rudrappa
Laxmi Kokatnur
Sanket Shah
Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
F1000Research
title Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
title_full Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
title_fullStr Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
title_full_unstemmed Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
title_short Case Report: Upper airway obstruction due to rheumatoid arthritis [version 1; peer review: 2 approved]
title_sort case report upper airway obstruction due to rheumatoid arthritis version 1 peer review 2 approved
url https://f1000research.com/articles/9-119/v1
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AT sanketshah casereportupperairwayobstructionduetorheumatoidarthritisversion1peerreview2approved