Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma

Background: Airway mucus hypersecretion is an important pathophysiological feature of asthma. MUC5AC and MUC5B are the major secreted polymeric mucins in airways, and their compositions affect mucus properties. Despite the increasing appreciation of MUC5AC and MUC5B compositions in asthmatic airways...

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Bibliographic Details
Main Authors: Tomoko Tajiri, Hisako Matsumoto, Makiko Jinnai, Yoshihiro Kanemitsu, Tadao Nagasaki, Toshiyuki Iwata, Hideki Inoue, Hitoshi Nakaji, Tsuyoshi Oguma, Isao Ito, Akio Niimi
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Allergology International
Subjects:
Airway hyperresponsiveness
Airway hypersecretion
Asthma
MUC5AC
MUC5B
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893021001234

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