Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment
Background and purpose: Fatty liver is one of the most common liver diseases. Some treatments used in breast cancer may be associated with development of fatty liver. The present study aimed at investigating the prevalence of fatty liver in breast cancer patients. Materials and methods: In this cros...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mazandaran University of Medical Sciences
2023-04-01
|
| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-18952-en.html |
| _version_ | 1797561905094590464 |
|---|---|
| author | Shahrbanoo Keyhanian Faezeh Bahman-tajani Ali Saravi Sara Esmaeil taleshian Zahra Fotokian |
| author_facet | Shahrbanoo Keyhanian Faezeh Bahman-tajani Ali Saravi Sara Esmaeil taleshian Zahra Fotokian |
| author_sort | Shahrbanoo Keyhanian |
| collection | DOAJ |
| description | Background and purpose: Fatty liver is one of the most common liver diseases. Some treatments used in breast cancer may be associated with development of fatty liver. The present study aimed at investigating the prevalence of fatty liver in breast cancer patients.
Materials and methods: In this cross-sectional study, 117 patients with breast cancer attending Ramsar Imam Sajjad Hospital in 2017-2022 were selected using available sampling. Patients who had fatty liver before the treatment or had a history of alcohol consumption were excluded from the study. Relevant information, including age, BMI, underlying diseases, time since cancer diagnosis, type of treatment/s, and liver enzyme levels were obtained. Liver ultrasound and measurement of liver enzyme levels were done to study fatty liver. Data were analyzed in SPSS V26 applying Chi-square test.
Results: According to findings, 54.7% of the patients were suffering from fatty liver. The majority had Grade I fatty liver. Among the patients 53.8% received all four types of treatments (surgery, chemotherapy, hormone therapy, and radiotherapy). The study showed significant relationships between the incidence of fatty liver and type of treatment, underlying disease, liver enzyme levels, and duration of breast cancer (P<0.05).
Conclusion: Non-alcoholic fatty liver is seen in many patients with breast cancer. Treatment methods used in these patients are associated with the development of fatty liver. Therefore, clinicians are suggested to use appropriate diagnostic and treatment methods for fatty liver to reduce the incidence of complications caused by this condition in patients with breast cancer. |
| first_indexed | 2024-03-10T18:21:13Z |
| format | Article |
| id | doaj.art-d4a52e6e2e0a42689e19f89a7dcea567 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-03-10T18:21:13Z |
| publishDate | 2023-04-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-d4a52e6e2e0a42689e19f89a7dcea5672023-11-20T07:20:18ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792023-04-01332199299Prevalence of Fatty Liver in Breast Cancer Patients Undergoing TreatmentShahrbanoo Keyhanian0Faezeh Bahman-tajani1Ali Saravi2Sara Esmaeil taleshian3Zahra Fotokian4 Associate Professor, Department of Medicine, Faculty of Medicine, Islamic Azad University, Tonekabon Branch, Toneklabon, Iran Medical Student, Faculty of Medicine, Islamic Azad University, Tonekabon Branch, Toneklabon, Iran General Practitioner, I.R.I Police HQ, Tehran, Iran BSc in Nursing, Ramsar Imam Sajjad Hospital, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Nursing Care Research Center, Babol University of Medical Sciences, Babol, Iran Background and purpose: Fatty liver is one of the most common liver diseases. Some treatments used in breast cancer may be associated with development of fatty liver. The present study aimed at investigating the prevalence of fatty liver in breast cancer patients. Materials and methods: In this cross-sectional study, 117 patients with breast cancer attending Ramsar Imam Sajjad Hospital in 2017-2022 were selected using available sampling. Patients who had fatty liver before the treatment or had a history of alcohol consumption were excluded from the study. Relevant information, including age, BMI, underlying diseases, time since cancer diagnosis, type of treatment/s, and liver enzyme levels were obtained. Liver ultrasound and measurement of liver enzyme levels were done to study fatty liver. Data were analyzed in SPSS V26 applying Chi-square test. Results: According to findings, 54.7% of the patients were suffering from fatty liver. The majority had Grade I fatty liver. Among the patients 53.8% received all four types of treatments (surgery, chemotherapy, hormone therapy, and radiotherapy). The study showed significant relationships between the incidence of fatty liver and type of treatment, underlying disease, liver enzyme levels, and duration of breast cancer (P<0.05). Conclusion: Non-alcoholic fatty liver is seen in many patients with breast cancer. Treatment methods used in these patients are associated with the development of fatty liver. Therefore, clinicians are suggested to use appropriate diagnostic and treatment methods for fatty liver to reduce the incidence of complications caused by this condition in patients with breast cancer.http://jmums.mazums.ac.ir/article-1-18952-en.htmlnon-alcoholic fatty liverbreast cancerbreast cancer treatment methods |
| spellingShingle | Shahrbanoo Keyhanian Faezeh Bahman-tajani Ali Saravi Sara Esmaeil taleshian Zahra Fotokian Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment Journal of Mazandaran University of Medical Sciences non-alcoholic fatty liver breast cancer breast cancer treatment methods |
| title | Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment |
| title_full | Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment |
| title_fullStr | Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment |
| title_full_unstemmed | Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment |
| title_short | Prevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment |
| title_sort | prevalence of fatty liver in breast cancer patients undergoing treatment |
| topic | non-alcoholic fatty liver breast cancer breast cancer treatment methods |
| url | http://jmums.mazums.ac.ir/article-1-18952-en.html |
| work_keys_str_mv | AT shahrbanookeyhanian prevalenceoffattyliverinbreastcancerpatientsundergoingtreatment AT faezehbahmantajani prevalenceoffattyliverinbreastcancerpatientsundergoingtreatment AT alisaravi prevalenceoffattyliverinbreastcancerpatientsundergoingtreatment AT saraesmaeiltaleshian prevalenceoffattyliverinbreastcancerpatientsundergoingtreatment AT zahrafotokian prevalenceoffattyliverinbreastcancerpatientsundergoingtreatment |