Therapeutic Strategies for IVD Regeneration through Hyaluronan/SDF-1-Based Hydrogel and Intravenous Administration of MSCs

Therapeutic Strategies for IVD Regeneration through Hyaluronan/SDF-1-Based Hydrogel and Intravenous Administration of MSCs

Intervertebral disc (IVD) degeneration involves a complex cascade of events, including degradation of the native extracellular matrix, loss of water content, and decreased cell numbers. Cell recruitment strategies for the IVD have been increasingly explored, aiming to recruit either endogenous or tr...

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Bibliographic Details
Main Authors: Carla Cunha, Catarina Leite Pereira, Joana R. Ferreira, Cláudia Ribeiro-Machado, Sibylle Grad, Susana G. Santos, Raquel M. Gonçalves
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
intervertebral disc
MSCs
recruitment
biomaterials
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/17/9609

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