Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors
Introduction Survivors of critical illness stay frequently experience long-term mental health morbidity, suggesting that many critically ill patients with COVID-19 may also show a high prevalence of psychiatric conditions. Objectives To describe depression in COVID-19 survivors 4-months post-hos...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821006921/type/journal_article |
| _version_ | 1797616328824061952 |
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| author | S. Martins A.R. Ferreira J. Fernandes T. Vieira L. Fontes I. Coimbra J. Paiva L. Fernandes |
| author_facet | S. Martins A.R. Ferreira J. Fernandes T. Vieira L. Fontes I. Coimbra J. Paiva L. Fernandes |
| author_sort | S. Martins |
| collection | DOAJ |
| description |
Introduction
Survivors of critical illness stay frequently experience long-term mental health morbidity, suggesting that many critically ill patients with COVID-19 may also show a high prevalence of psychiatric conditions.
Objectives
To describe depression in COVID-19 survivors 4-months post-hospital discharge and to examine its association with health-related quality of life (HRQoL).
Methods
This pilot study involved COVID-19 adult patients admitted in Intensive Care Medicine Service (ICMS) of a University Hospital. Exclusion criteria were: ICMS length of stay (LoS)≤24h, terminal illness, major sensory loss and inability to communicate at the time of assessment. All participants were evaluated at ICMS scheduled telephone follow-up appointment, with Patient Health Questionnaire (PHQ-9) (depression) and EQ-5D-5L (HRQoL). Critical-illness severity was assessed with APACHE-II and SAPS-II.
Results
Twenty patients were included with a median age of 62(range: 24-77) y.o., the majority male (75%) and married (70%). Median (range) APACHE-II and SAPS-II was 17 (5-34) and 32.5 (7-77), respectively, and LoS was 18 (4-58) days. Overall, 25% patients presented depression symptoms and most reported problems on EQ-5D-5L domains of pain/discomfort (65%), anxiety/depression (55%) and mobility (50%). Depression scores were higher in patients with problems in EQ-5D-5L domains of usual activities (median 4 vs 1.5; p=0.046), pain/discomfort (median 0 vs 4; p=0.004) and anxiety/depression (median 4 vs 0;p<0.001).
Conclusions
These preliminary findings show that depression is frequent in COVID-19 survivors and it is associated with worse HRQoL. This pilot study highlights the importance of psychological assessment and treatment of COVID-19 survivors, in order to minimize its negative impact on HRQoL, optimizing their recovery.
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| first_indexed | 2024-03-11T07:39:29Z |
| format | Article |
| id | doaj.art-d4ab5b6040834f8fa0a9a689332ccc13 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:39:29Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-d4ab5b6040834f8fa0a9a689332ccc132023-11-17T05:08:55ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S258S25810.1192/j.eurpsy.2021.692Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivorsS. Martins0A.R. Ferreira1J. Fernandes2T. Vieira3L. Fontes4I. Coimbra5J. Paiva6L. Fernandes7Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Faculty of Medicine - University Porto, Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, PortugalIntensive Care Medicine Department, Centro Hospitalar Universitário São João (CHUSJ), Porto, Portugal Department Of Medicine, Faculty of Medicine - University Porto, Porto, PortugalPsychiatry Service, Centro Hospitalar Universitário São João (CHUSJ), Porto, Portugal Introduction Survivors of critical illness stay frequently experience long-term mental health morbidity, suggesting that many critically ill patients with COVID-19 may also show a high prevalence of psychiatric conditions. Objectives To describe depression in COVID-19 survivors 4-months post-hospital discharge and to examine its association with health-related quality of life (HRQoL). Methods This pilot study involved COVID-19 adult patients admitted in Intensive Care Medicine Service (ICMS) of a University Hospital. Exclusion criteria were: ICMS length of stay (LoS)≤24h, terminal illness, major sensory loss and inability to communicate at the time of assessment. All participants were evaluated at ICMS scheduled telephone follow-up appointment, with Patient Health Questionnaire (PHQ-9) (depression) and EQ-5D-5L (HRQoL). Critical-illness severity was assessed with APACHE-II and SAPS-II. Results Twenty patients were included with a median age of 62(range: 24-77) y.o., the majority male (75%) and married (70%). Median (range) APACHE-II and SAPS-II was 17 (5-34) and 32.5 (7-77), respectively, and LoS was 18 (4-58) days. Overall, 25% patients presented depression symptoms and most reported problems on EQ-5D-5L domains of pain/discomfort (65%), anxiety/depression (55%) and mobility (50%). Depression scores were higher in patients with problems in EQ-5D-5L domains of usual activities (median 4 vs 1.5; p=0.046), pain/discomfort (median 0 vs 4; p=0.004) and anxiety/depression (median 4 vs 0;p<0.001). Conclusions These preliminary findings show that depression is frequent in COVID-19 survivors and it is associated with worse HRQoL. This pilot study highlights the importance of psychological assessment and treatment of COVID-19 survivors, in order to minimize its negative impact on HRQoL, optimizing their recovery. https://www.cambridge.org/core/product/identifier/S0924933821006921/type/journal_articleCOVID-19ICU survivorsDepressionquality of life |
| spellingShingle | S. Martins A.R. Ferreira J. Fernandes T. Vieira L. Fontes I. Coimbra J. Paiva L. Fernandes Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors European Psychiatry COVID-19 ICU survivors Depression quality of life |
| title | Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors |
| title_full | Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors |
| title_fullStr | Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors |
| title_full_unstemmed | Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors |
| title_short | Post-discharge depressive symptoms and health-related quality of life of critical COVID-19 survivors |
| title_sort | post discharge depressive symptoms and health related quality of life of critical covid 19 survivors |
| topic | COVID-19 ICU survivors Depression quality of life |
| url | https://www.cambridge.org/core/product/identifier/S0924933821006921/type/journal_article |
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