Investigation of mesalazine as an antifibrotic drug following myocardial infarction in male mice

Investigation of mesalazine as an antifibrotic drug following myocardial infarction in male mice

Abstract Objectives Myocardial infarction (MI) initiates a complex reparative response during which damaged cardiac muscle is replaced by connective tissue. While the initial repair is essential for survival, excessive fibrosis post‐MI is a primary contributor to progressive cardiac dysfunction, and...

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Bibliographic Details
Main Authors: Stephan R. Künzel, Luise Winter, Maximilian Hoffmann, Theresa A. Kant, Jessica Thiel, Romy Kronstein‐Wiedemann, Erik Klapproth, Kristina Lorenz, Ali El‐Armouche, Susanne Kämmerer
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Physiological Reports
Subjects:
drug repurposing
fibrosis
mesalazine
myocardial infarction
Online Access:https://doi.org/10.14814/phy2.15809

Internet

https://doi.org/10.14814/phy2.15809

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