Crusted scabies-associated immune reconstitution inflammatory syndrome
<p>Abstract</p> <p>Background</p> <p>Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory...
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| Format: | Article |
| Language: | English |
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BMC
2012-11-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-2334/12/323 |
| _version_ | 1831737174572138496 |
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| author | Fernández-Sánchez Mónica Saeb-Lima Marcela Alvarado-de la Barrera Claudia Reyes-Terán Gustavo |
| author_facet | Fernández-Sánchez Mónica Saeb-Lima Marcela Alvarado-de la Barrera Claudia Reyes-Terán Gustavo |
| author_sort | Fernández-Sánchez Mónica |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory syndrome in HIV-infected patients initiating antiretroviral therapy.</p> <p>Case presentation</p> <p>We report a case of a 28-year-old Mexican individual with late HIV-infection, who had no apparent skin lesions but soon after initiation of antiretroviral therapy, he developed an aggressive form of crusted scabies with rapid progression of lesions. Severe infestation by <it>Sarcoptes scabiei</it> was confirmed by microscopic examination of the scale and skin biopsy. Due to the atypical presentation of scabies in a patient responding to antiretroviral therapy, preceded by no apparent skin lesions at initiation of antiretroviral therapy, the episode was interpreted for the first time as “unmasking crusted scabies-associated immune reconstitution inflammatory syndrome”.</p> <p>Conclusion</p> <p>This case illustrates that when crusted scabies is observed in HIV-infected patients responding to antiretroviral therapy, it might as well be considered as a possible manifestation of immune reconstitution inflammatory syndrome. Patient context should be considered for adequate diagnosis and treatment of conditions exacerbated by antiretroviral therapy-induced immune reconstitution.</p> |
| first_indexed | 2024-12-21T12:58:10Z |
| format | Article |
| id | doaj.art-d4afef05ca2b411e88b846ed65635f69 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-21T12:58:10Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-d4afef05ca2b411e88b846ed65635f692022-12-21T19:03:16ZengBMCBMC Infectious Diseases1471-23342012-11-0112132310.1186/1471-2334-12-323Crusted scabies-associated immune reconstitution inflammatory syndromeFernández-Sánchez MónicaSaeb-Lima MarcelaAlvarado-de la Barrera ClaudiaReyes-Terán Gustavo<p>Abstract</p> <p>Background</p> <p>Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory syndrome in HIV-infected patients initiating antiretroviral therapy.</p> <p>Case presentation</p> <p>We report a case of a 28-year-old Mexican individual with late HIV-infection, who had no apparent skin lesions but soon after initiation of antiretroviral therapy, he developed an aggressive form of crusted scabies with rapid progression of lesions. Severe infestation by <it>Sarcoptes scabiei</it> was confirmed by microscopic examination of the scale and skin biopsy. Due to the atypical presentation of scabies in a patient responding to antiretroviral therapy, preceded by no apparent skin lesions at initiation of antiretroviral therapy, the episode was interpreted for the first time as “unmasking crusted scabies-associated immune reconstitution inflammatory syndrome”.</p> <p>Conclusion</p> <p>This case illustrates that when crusted scabies is observed in HIV-infected patients responding to antiretroviral therapy, it might as well be considered as a possible manifestation of immune reconstitution inflammatory syndrome. Patient context should be considered for adequate diagnosis and treatment of conditions exacerbated by antiretroviral therapy-induced immune reconstitution.</p>http://www.biomedcentral.com/1471-2334/12/323Crusted scabiesIRISHIVAIDSART |
| spellingShingle | Fernández-Sánchez Mónica Saeb-Lima Marcela Alvarado-de la Barrera Claudia Reyes-Terán Gustavo Crusted scabies-associated immune reconstitution inflammatory syndrome BMC Infectious Diseases Crusted scabies IRIS HIV AIDS ART |
| title | Crusted scabies-associated immune reconstitution inflammatory syndrome |
| title_full | Crusted scabies-associated immune reconstitution inflammatory syndrome |
| title_fullStr | Crusted scabies-associated immune reconstitution inflammatory syndrome |
| title_full_unstemmed | Crusted scabies-associated immune reconstitution inflammatory syndrome |
| title_short | Crusted scabies-associated immune reconstitution inflammatory syndrome |
| title_sort | crusted scabies associated immune reconstitution inflammatory syndrome |
| topic | Crusted scabies IRIS HIV AIDS ART |
| url | http://www.biomedcentral.com/1471-2334/12/323 |
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