Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors

Background: Depression affects millions worldwide, with drug therapy being the mainstay treatment. A variety of factors, including personal reviews, are involved in the success or failure of medication therapy. This study looked to characterize the sentiment of online medication reviews of Selective...

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Main Authors: Chad Compagner, Corey Lester, Michael Dorsch
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmacy
Subjects:
Online Access:https://www.mdpi.com/2226-4787/9/1/27
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author Chad Compagner
Corey Lester
Michael Dorsch
author_facet Chad Compagner
Corey Lester
Michael Dorsch
author_sort Chad Compagner
collection DOAJ
description Background: Depression affects millions worldwide, with drug therapy being the mainstay treatment. A variety of factors, including personal reviews, are involved in the success or failure of medication therapy. This study looked to characterize the sentiment of online medication reviews of Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin–Norepinephrine Reuptake Inhibitor (SNRIs) used to treat depression. Methods: The publicly available data source used was the Drug Review Dataset from the University of California Irvine Machine Learning Repository. The dataset contained the following variables: ID, drug name, condition, review, rating, date, and usefulness count. This study utilized a sentiment analysis of free-text, online reviews via the sentimentr package. A Mann–Whitney U test was used for comparisons. Results: The average sentiment was higher in SSRIs compared to SNRIs (0.065 vs. 0.005, <i>p</i> < 0.001). The average sentiment was also found to be higher in high-rated reviews than in low-rated reviews (0.169 vs. −0.367, <i>p</i> < 0.001). Ratings were similar in the high-rated SSRI group and high-rated SNRI group (9.19 vs. 9.19). Conclusions: This study supports the use of sentiment analysis using the AFINN lexicon, as the lexicon showed a difference in sentiment between high-rated reviews from low-rated reviews. This study also found that SNRIs have more negative sentiment and lower-rated reviews than SSRIs.
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spelling doaj.art-d4b0fe263c4b4217a54cd21193d581e22023-12-03T14:25:31ZengMDPI AGPharmacy2226-47872021-01-01912710.3390/pharmacy9010027Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake InhibitorsChad Compagner0Corey Lester1Michael Dorsch2College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USACollege of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USACollege of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USABackground: Depression affects millions worldwide, with drug therapy being the mainstay treatment. A variety of factors, including personal reviews, are involved in the success or failure of medication therapy. This study looked to characterize the sentiment of online medication reviews of Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin–Norepinephrine Reuptake Inhibitor (SNRIs) used to treat depression. Methods: The publicly available data source used was the Drug Review Dataset from the University of California Irvine Machine Learning Repository. The dataset contained the following variables: ID, drug name, condition, review, rating, date, and usefulness count. This study utilized a sentiment analysis of free-text, online reviews via the sentimentr package. A Mann–Whitney U test was used for comparisons. Results: The average sentiment was higher in SSRIs compared to SNRIs (0.065 vs. 0.005, <i>p</i> < 0.001). The average sentiment was also found to be higher in high-rated reviews than in low-rated reviews (0.169 vs. −0.367, <i>p</i> < 0.001). Ratings were similar in the high-rated SSRI group and high-rated SNRI group (9.19 vs. 9.19). Conclusions: This study supports the use of sentiment analysis using the AFINN lexicon, as the lexicon showed a difference in sentiment between high-rated reviews from low-rated reviews. This study also found that SNRIs have more negative sentiment and lower-rated reviews than SSRIs.https://www.mdpi.com/2226-4787/9/1/27sentimentantidepressantdepressionemotionSSRISNRI
spellingShingle Chad Compagner
Corey Lester
Michael Dorsch
Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
Pharmacy
sentiment
antidepressant
depression
emotion
SSRI
SNRI
title Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
title_full Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
title_fullStr Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
title_full_unstemmed Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
title_short Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors
title_sort sentiment analysis of online reviews for selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors
topic sentiment
antidepressant
depression
emotion
SSRI
SNRI
url https://www.mdpi.com/2226-4787/9/1/27
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AT michaeldorsch sentimentanalysisofonlinereviewsforselectiveserotoninreuptakeinhibitorsandserotoninnorepinephrinereuptakeinhibitors