134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model
OBJECTIVES/GOALS: The Translational Science Benefits Model (TSBM), developed at Washington University in St. Louis, was used to create a survey to collect group-level data on the real-world impacts of research. It was used with two cohorts of CTSA-supported pilot studies to compare the benefits of c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-04-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866123002169/type/journal_article |
| _version_ | 1797840504936726528 |
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| author | Nicole Miovsky Amanda Woodworth Margaret Schneider |
| author_facet | Nicole Miovsky Amanda Woodworth Margaret Schneider |
| author_sort | Nicole Miovsky |
| collection | DOAJ |
| description | OBJECTIVES/GOALS: The Translational Science Benefits Model (TSBM), developed at Washington University in St. Louis, was used to create a survey to collect group-level data on the real-world impacts of research. It was used with two cohorts of CTSA-supported pilot studies to compare the benefits of campus-community partnerships to campus-only projects. METHODS/STUDY POPULATION: Investigators from two funding streams were surveyed: a campus-based cohort (n=31), and a campus-community partnership cohort (n=6). All studies were related to COVID-19. The Translational Benefits Survey collected quantitative and qualitative data for each of the 30 TSBM benefits, in 4 benefit categories: clinical, community, economic and policy. Text provided by investigators to support each reported benefit was evaluated by two coders through a process that required coder consensus to verify a benefit as realized. Verified benefits were aggregated for each cohort, and the percentage of projects per cohort with realized clinical, community, economic and policy benefits were calculated. RESULTS/ANTICIPATED RESULTS: Campus-community partnerships did not realize any clinical benefits, whereas 26% of campus-based projects realized at least one clinical benefit. In contrast, campus-community partnerships were more likely to realize community health benefits (17% vs 10% of campus projects) and economic benefits (17% vs 13% of campus projects). We identified a substantial amount of self-reported benefits (64% across all categories) that were unable to be confirmed as realized using the provided text, which either described activities not relevant to the selected benefit, or lacked critical details needed to verify that the benefit was realized. DISCUSSION/SIGNIFICANCE: This project demonstrates that the TSBM can be utilized to collect group-level data and to compare cohorts’real-world benefits. It also illuminates the need to improve the process for verifying self-reported benefits. Sharing data on these real-world impacts has the potential to convey the strengths of translational science to the public. |
| first_indexed | 2024-04-09T16:16:25Z |
| format | Article |
| id | doaj.art-d4b34203e3ad4ee6a511084ac9a56110 |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-04-09T16:16:25Z |
| publishDate | 2023-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-d4b34203e3ad4ee6a511084ac9a561102023-04-24T05:55:54ZengCambridge University PressJournal of Clinical and Translational Science2059-86612023-04-017404110.1017/cts.2023.216134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits ModelNicole Miovsky0Amanda Woodworth1Margaret Schneider2Institute for Clinical and Translational Science, University of California at IrvineInstitute for Clinical and Translational Science, University of California at IrvineInstitute for Clinical and Translational Science, University of California at IrvineOBJECTIVES/GOALS: The Translational Science Benefits Model (TSBM), developed at Washington University in St. Louis, was used to create a survey to collect group-level data on the real-world impacts of research. It was used with two cohorts of CTSA-supported pilot studies to compare the benefits of campus-community partnerships to campus-only projects. METHODS/STUDY POPULATION: Investigators from two funding streams were surveyed: a campus-based cohort (n=31), and a campus-community partnership cohort (n=6). All studies were related to COVID-19. The Translational Benefits Survey collected quantitative and qualitative data for each of the 30 TSBM benefits, in 4 benefit categories: clinical, community, economic and policy. Text provided by investigators to support each reported benefit was evaluated by two coders through a process that required coder consensus to verify a benefit as realized. Verified benefits were aggregated for each cohort, and the percentage of projects per cohort with realized clinical, community, economic and policy benefits were calculated. RESULTS/ANTICIPATED RESULTS: Campus-community partnerships did not realize any clinical benefits, whereas 26% of campus-based projects realized at least one clinical benefit. In contrast, campus-community partnerships were more likely to realize community health benefits (17% vs 10% of campus projects) and economic benefits (17% vs 13% of campus projects). We identified a substantial amount of self-reported benefits (64% across all categories) that were unable to be confirmed as realized using the provided text, which either described activities not relevant to the selected benefit, or lacked critical details needed to verify that the benefit was realized. DISCUSSION/SIGNIFICANCE: This project demonstrates that the TSBM can be utilized to collect group-level data and to compare cohorts’real-world benefits. It also illuminates the need to improve the process for verifying self-reported benefits. Sharing data on these real-world impacts has the potential to convey the strengths of translational science to the public.https://www.cambridge.org/core/product/identifier/S2059866123002169/type/journal_article |
| spellingShingle | Nicole Miovsky Amanda Woodworth Margaret Schneider 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model Journal of Clinical and Translational Science |
| title | 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model |
| title_full | 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model |
| title_fullStr | 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model |
| title_full_unstemmed | 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model |
| title_short | 134 Comparing Real-World Impacts of Cohorts using the Translational Science Benefits Model |
| title_sort | 134 comparing real world impacts of cohorts using the translational science benefits model |
| url | https://www.cambridge.org/core/product/identifier/S2059866123002169/type/journal_article |
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