Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation
Breast-conserving surgery (BCS) with negative resection margins decreases the locoregional recurrence rate. Breast cancer size is one of the main determinants of Tumor-Node-Metastasis (TNM) staging. Our study aimed to investigate the accuracy of supine 3D automated breast ultrasound (3D ABUS) compar...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Tomography |
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| Online Access: | https://www.mdpi.com/2379-139X/8/4/167 |
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| author | Anna D’Angelo Gianluca Gatta Graziella Di Grezia Sara Mercogliano Francesca Ferrara Charlotte Marguerite Lucille Trombadori Antonio Franco Alessandro Cina Paolo Belli Riccardo Manfredi |
| author_facet | Anna D’Angelo Gianluca Gatta Graziella Di Grezia Sara Mercogliano Francesca Ferrara Charlotte Marguerite Lucille Trombadori Antonio Franco Alessandro Cina Paolo Belli Riccardo Manfredi |
| author_sort | Anna D’Angelo |
| collection | DOAJ |
| description | Breast-conserving surgery (BCS) with negative resection margins decreases the locoregional recurrence rate. Breast cancer size is one of the main determinants of Tumor-Node-Metastasis (TNM) staging. Our study aimed to investigate the accuracy of supine 3D automated breast ultrasound (3D ABUS) compared to prone 3D ABUS in the evaluation of tumor size in breast cancer patient candidates for BCS. In this prospective two-center study (Groups 1 and 2), we enrolled patients with percutaneous biopsy-proven early-stage breast cancer, in the period between June 2019 and May 2020. Patients underwent hand-held ultrasound (HHUS), contrast-enhanced magnetic resonance imaging (CE-MRI) and 3D ABUS—supine 3D ABUS in Group 1 and prone 3D ABUS in Group 2. Histopathological examination (HE) was considered the reference standard. Bland–Altman analysis and plots were used. Eighty-eight patients were enrolled. Compared to prone, supine 3D ABUS showed better agreement with HE, with a slight tendency toward underestimation (mean difference of −2 mm). Supine 3D ABUS appears to be a useful tool and more accurate than HHUS in the staging of breast cancer. |
| first_indexed | 2024-03-10T01:55:22Z |
| format | Article |
| id | doaj.art-d4b90f8cb3514c95a6abebdb2fc715f1 |
| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-10T01:55:22Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-d4b90f8cb3514c95a6abebdb2fc715f12023-11-23T12:59:09ZengMDPI AGTomography2379-13812379-139X2022-08-01841997200910.3390/tomography8040167Supine versus Prone 3D Abus Accuracy in Breast Tumor Size EvaluationAnna D’Angelo0Gianluca Gatta1Graziella Di Grezia2Sara Mercogliano3Francesca Ferrara4Charlotte Marguerite Lucille Trombadori5Antonio Franco6Alessandro Cina7Paolo Belli8Riccardo Manfredi9Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyDipartimento di Medicina di Precisione, Università degli Studi della Campania “L. Vanvitelli”, 80138 Naples, ItalyDipartimento di Radiologia, Ospedale “G. Criscuoli”, 83054 San’Angelo dei Lombardi, ItalyCasa di Cura Villa dei Fiori, 80011 Acerra, ItalyDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyUnità di Senologia, Dipartimento della Donna, del Bambino e di Salute Pubblica, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyBreast-conserving surgery (BCS) with negative resection margins decreases the locoregional recurrence rate. Breast cancer size is one of the main determinants of Tumor-Node-Metastasis (TNM) staging. Our study aimed to investigate the accuracy of supine 3D automated breast ultrasound (3D ABUS) compared to prone 3D ABUS in the evaluation of tumor size in breast cancer patient candidates for BCS. In this prospective two-center study (Groups 1 and 2), we enrolled patients with percutaneous biopsy-proven early-stage breast cancer, in the period between June 2019 and May 2020. Patients underwent hand-held ultrasound (HHUS), contrast-enhanced magnetic resonance imaging (CE-MRI) and 3D ABUS—supine 3D ABUS in Group 1 and prone 3D ABUS in Group 2. Histopathological examination (HE) was considered the reference standard. Bland–Altman analysis and plots were used. Eighty-eight patients were enrolled. Compared to prone, supine 3D ABUS showed better agreement with HE, with a slight tendency toward underestimation (mean difference of −2 mm). Supine 3D ABUS appears to be a useful tool and more accurate than HHUS in the staging of breast cancer.https://www.mdpi.com/2379-139X/8/4/1673D automated breast ultrasound (ABUS)breast cancerhand-held ultrasound (HHUS)magnetic resonance imaging (MRI)breast imaging |
| spellingShingle | Anna D’Angelo Gianluca Gatta Graziella Di Grezia Sara Mercogliano Francesca Ferrara Charlotte Marguerite Lucille Trombadori Antonio Franco Alessandro Cina Paolo Belli Riccardo Manfredi Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation Tomography 3D automated breast ultrasound (ABUS) breast cancer hand-held ultrasound (HHUS) magnetic resonance imaging (MRI) breast imaging |
| title | Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation |
| title_full | Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation |
| title_fullStr | Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation |
| title_full_unstemmed | Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation |
| title_short | Supine versus Prone 3D Abus Accuracy in Breast Tumor Size Evaluation |
| title_sort | supine versus prone 3d abus accuracy in breast tumor size evaluation |
| topic | 3D automated breast ultrasound (ABUS) breast cancer hand-held ultrasound (HHUS) magnetic resonance imaging (MRI) breast imaging |
| url | https://www.mdpi.com/2379-139X/8/4/167 |
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