Epidemiology of viral hepatitis in Sudan

Hatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the v...

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Main Author: Hatim MY Mudawi
Format: Article
Language:English
Published: Dove Medical Press 2008-11-01
Series:Clinical and Experimental Gastroenterology
Online Access:http://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565
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author Hatim MY Mudawi
author_facet Hatim MY Mudawi
author_sort Hatim MY Mudawi
collection DOAJ
description Hatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%–78%, with a hepatitis B surface antigen prevalence ranging from 6.8% in central Sudan to 26% in southern Sudan. Studies pointed to infection in early childhood in southern Sudan while there was a trend of increasing infection rate with increasing age in northern Sudan. Hepatitis B virus was the commonest cause of chronic liver disease and hepatocellular carcinoma and was the second commonest cause of acute liver failure in the Sudan. Studies of hepatitis C virus showed a low seroprevalence of 2.2%–4.8% and there was no association with schistosomiasis or with parenteral antischistosomal therapy. Hepatitis E virus was the commonest cause of acute hepatitis among pediatric, adult, and displaced populations. Recent introduction of screening of blood and blood products for hepatitis B virus and hepatitis C virus infections and the introduction of hepatitis B virus vaccine as part of the extended program of immunization is expected to reduce the infection rate of these viruses in the Sudan.Keywords: hepatitis, Sudan, liver disease
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spelling doaj.art-d4c1899a695744ce80f4e14584bd977d2022-12-22T01:47:25ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232008-11-012008default913Epidemiology of viral hepatitis in SudanHatim MY MudawiHatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%–78%, with a hepatitis B surface antigen prevalence ranging from 6.8% in central Sudan to 26% in southern Sudan. Studies pointed to infection in early childhood in southern Sudan while there was a trend of increasing infection rate with increasing age in northern Sudan. Hepatitis B virus was the commonest cause of chronic liver disease and hepatocellular carcinoma and was the second commonest cause of acute liver failure in the Sudan. Studies of hepatitis C virus showed a low seroprevalence of 2.2%–4.8% and there was no association with schistosomiasis or with parenteral antischistosomal therapy. Hepatitis E virus was the commonest cause of acute hepatitis among pediatric, adult, and displaced populations. Recent introduction of screening of blood and blood products for hepatitis B virus and hepatitis C virus infections and the introduction of hepatitis B virus vaccine as part of the extended program of immunization is expected to reduce the infection rate of these viruses in the Sudan.Keywords: hepatitis, Sudan, liver diseasehttp://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565
spellingShingle Hatim MY Mudawi
Epidemiology of viral hepatitis in Sudan
Clinical and Experimental Gastroenterology
title Epidemiology of viral hepatitis in Sudan
title_full Epidemiology of viral hepatitis in Sudan
title_fullStr Epidemiology of viral hepatitis in Sudan
title_full_unstemmed Epidemiology of viral hepatitis in Sudan
title_short Epidemiology of viral hepatitis in Sudan
title_sort epidemiology of viral hepatitis in sudan
url http://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565
work_keys_str_mv AT hatimmymudawi epidemiologyofviralhepatitisinsudan