Epidemiology of viral hepatitis in Sudan
Hatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the v...
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Format: | Article |
Language: | English |
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Dove Medical Press
2008-11-01
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Series: | Clinical and Experimental Gastroenterology |
Online Access: | http://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565 |
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author | Hatim MY Mudawi |
author_facet | Hatim MY Mudawi |
author_sort | Hatim MY Mudawi |
collection | DOAJ |
description | Hatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%–78%, with a hepatitis B surface antigen prevalence ranging from 6.8% in central Sudan to 26% in southern Sudan. Studies pointed to infection in early childhood in southern Sudan while there was a trend of increasing infection rate with increasing age in northern Sudan. Hepatitis B virus was the commonest cause of chronic liver disease and hepatocellular carcinoma and was the second commonest cause of acute liver failure in the Sudan. Studies of hepatitis C virus showed a low seroprevalence of 2.2%–4.8% and there was no association with schistosomiasis or with parenteral antischistosomal therapy. Hepatitis E virus was the commonest cause of acute hepatitis among pediatric, adult, and displaced populations. Recent introduction of screening of blood and blood products for hepatitis B virus and hepatitis C virus infections and the introduction of hepatitis B virus vaccine as part of the extended program of immunization is expected to reduce the infection rate of these viruses in the Sudan.Keywords: hepatitis, Sudan, liver disease |
first_indexed | 2024-12-10T13:19:30Z |
format | Article |
id | doaj.art-d4c1899a695744ce80f4e14584bd977d |
institution | Directory Open Access Journal |
issn | 1178-7023 |
language | English |
last_indexed | 2024-12-10T13:19:30Z |
publishDate | 2008-11-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Clinical and Experimental Gastroenterology |
spelling | doaj.art-d4c1899a695744ce80f4e14584bd977d2022-12-22T01:47:25ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232008-11-012008default913Epidemiology of viral hepatitis in SudanHatim MY MudawiHatim MY MudawiDepartment of Internal Medicine, Faculty of Medicine, University of Khartoum, Khartoum, SudanAbstract: Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%–78%, with a hepatitis B surface antigen prevalence ranging from 6.8% in central Sudan to 26% in southern Sudan. Studies pointed to infection in early childhood in southern Sudan while there was a trend of increasing infection rate with increasing age in northern Sudan. Hepatitis B virus was the commonest cause of chronic liver disease and hepatocellular carcinoma and was the second commonest cause of acute liver failure in the Sudan. Studies of hepatitis C virus showed a low seroprevalence of 2.2%–4.8% and there was no association with schistosomiasis or with parenteral antischistosomal therapy. Hepatitis E virus was the commonest cause of acute hepatitis among pediatric, adult, and displaced populations. Recent introduction of screening of blood and blood products for hepatitis B virus and hepatitis C virus infections and the introduction of hepatitis B virus vaccine as part of the extended program of immunization is expected to reduce the infection rate of these viruses in the Sudan.Keywords: hepatitis, Sudan, liver diseasehttp://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565 |
spellingShingle | Hatim MY Mudawi Epidemiology of viral hepatitis in Sudan Clinical and Experimental Gastroenterology |
title | Epidemiology of viral hepatitis in Sudan |
title_full | Epidemiology of viral hepatitis in Sudan |
title_fullStr | Epidemiology of viral hepatitis in Sudan |
title_full_unstemmed | Epidemiology of viral hepatitis in Sudan |
title_short | Epidemiology of viral hepatitis in Sudan |
title_sort | epidemiology of viral hepatitis in sudan |
url | http://www.dovepress.com/epidemiology-of-viral-hepatitis-in-sudan-a2565 |
work_keys_str_mv | AT hatimmymudawi epidemiologyofviralhepatitisinsudan |